Gastroesophageal Cancer During Pregnancy: a Case Report and Review of the Literature

  • Mustafa Bozkurt
  • Mara Antonoff
  • Sylvia Jaramillo
  • Tara Sagebiel
  • Mariela B. Murphy
Case Report


Incidence of cancer during pregnancy is likely increased nowadays in developed societies and clinical practice due to women’s increasing trend toward late childbirth [1]. While cancer develops in approximately 1 to 2 per 1000 pregnant women, the diagnosis of esophageal or gastric cancer during pregnancy or the lactation period is very rare, accounting for only 0.026 to 0.1% of all pregnancies [2]. Gastroesophageal junction (GEJ) cancer diagnosis during pregnancy is usually delayed due to low index of suspicion for having a malignant disease at a young age. Symptoms such as abdominal pain, nausea, vomiting, and fatigue can be mistaken as part of physiologic gestational symptoms and anemia as a laboratory finding. Additionally, this group of patients has some distinct features that may affect disease course such as being of young age, female gender, mostly being diagnosed at advanced stage, having a passive attitude toward treatment due to concerns about fetal health, and...


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Mustafa Bozkurt
    • 1
  • Mara Antonoff
    • 2
  • Sylvia Jaramillo
    • 3
  • Tara Sagebiel
    • 4
  • Mariela B. Murphy
    • 1
    • 5
  1. 1.Department of Gastrointestinal Medical OncologyThe University of Texas MD Anderson Cancer CenterHoustonUSA
  2. 2.Department of Thoracic and Cardiovascular SurgeryThe University of Texas MD Anderson Cancer CenterHoustonUSA
  3. 3.Department of Hematology-OncologyTexas OncologyAustinUSA
  4. 4.Department of Diagnostic ImagingThe University of Texas MD Anderson Cancer CenterHoustonUSA
  5. 5.Department of Gastrointestinal Medical OncologyThe University of Texas MD Anderson Cancer CenterHoustonUSA

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