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Recurrent Adult Intraabdominal Undifferentiated High-Grade Pleomorphic Sarcoma Infiltrated the Descending Colon: a Case Report and Review of the Literature

  • Xu Ziwei
  • Sun Yueming
Case Report
  • 12 Downloads

Introduction

Undifferentiated pleomorphic sarcoma (UPS), which was previously known as malignant fibrous histiocytoma (MFH), was first described in 1961 by Kauffman as a histiocytic tumor with storiform growth in children [1]. On the new 2013 WHO classification of soft-tissue tumors, a new class of “undifferentiated/unclassified sarcoma” was created, with the deletion of MFH replaced by UPS and attributed to this category. UPS is a type of malignant sarcoma that occurs most frequently in patients aged between 50 and 70 years [2], accounting for 28% of all soft-tissue sarcomas [3]. The major locations for UPS are the lower (49%) and upper extremities (19%), while tumors of the retroperitoneum and abdominal cavity account for 16%, and those of trunk account for 9% of the cases [4]. The histological morphology varies, but the classic form is composed of spindle-shaped and round cells. The prognosis for UPS is very poor because of its strong chances of regional invasiveness and distant...

Notes

Acknowledgements

A special thanks to Jinista Janvee Jankee for the writing assistance.

Statement of Authorship

We hereby certify that all work contained in this manuscript is truthful original work without fabrication, fraud, or plagiarism. This manuscript is not currently under consideration, in press or published elsewhere. We claim full responsibility for the contents of the manuscript.

Funding

This work was supported by a grant from the National Natural Science Foundation of China (No. 81400835).

Compliance with Ethical Standards

Ethical Approval

Not needed.

Conflict of Interest

The authors declare that they have no conflict of interest.

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© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of General SurgeryThe First Affiliated Hospital of Nanjing Medical UniversityNanjingChina

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