Clear Cell Sarcoma-Like Tumor of the Gastrointestinal Tract

  • Gokce Askan
  • Faruk Erdem Kombak
  • Ipek Erbarut Seven
  • Olca Basturk
Case Report


Clear cell sarcoma-like tumor of the gastrointestinal tract (CCSLGT) is a relatively recently described neoplasm usually arising from wall of the small intestine [1, 2, 3, 4, 5, 6]. Because of the rarity of CCSLGT as well as its overlapping histomorphologic and genetic features (EWSR1 rearrangement) with other gastrointestinal mesenchymal neoplasms, especially with clear cell sarcoma of soft tissue, rendering a diagnosis of CCSLGT might be challenging.

We herein report an ileal CCSLGT and discuss clinicopathological, immunohistochemical, and molecular features as well as differential diagnoses of CCSLGTs.

Case Report

A 28-year-old male patient presented with 20-lb weight loss, over the past 18 months, as well as occasional night sweat and fatigue. Upper and lower endoscopies did not reveal any lesions. However, CT scan showed wall thickening and a soft tissue mass in a loop of small intestine. The small intestine proximal to the lesion was fluid-filled and dilated,...


Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no conflict of interest.

Ethical approval

For this type of study, formal consent is not required.

This article does not contain any studies with animals performed by any of the authors.

Informed Consent

Informed consent was obtained from all individual participants included in the study


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Gokce Askan
    • 1
  • Faruk Erdem Kombak
    • 2
  • Ipek Erbarut Seven
    • 2
  • Olca Basturk
    • 1
  1. 1.Department of PathologyMemorial Sloan Kettering Cancer CenterNew YorkUSA
  2. 2.Department of PathologyMarmara University School of MedicineIstanbulTurkey

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