Late-Onset Lung Metastasis in Rectum Cancer Can Be Confused with Primary Lung Cancer; a Case Report and Literature Review

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  1. 1.

    Tjandra JJ, Chan MK. Follow-up after curative resection of colorectal cancer: a meta-analysis. Dis Colon Rectum. 2007;50:1783–99.

    Article  Google Scholar 

  2. 2.

    Manfredi S, Bouvier AM, Lepage C, Hatem C, Dancourt V, Faivre J. Incidence and patterns of recurrence after resection for cure of colonic cancer in a well defined population. Br J Surg. 2006;93:1115–22.

    CAS  Article  Google Scholar 

  3. 3.

    van Gestel YR, de Hingh IH, van Herk-Sukel MP, van Erning FN, Beerepoot LV, Wijsman JH, et al. Patterns of metachronous metastases after curative treatment of colorectal cancer. Cancer Epidemiol. 2014;38:448–54.

    Article  Google Scholar 

  4. 4.

    Chiang JM, Hsieh PS, Chen JS, Tang R, You JF, Yeh CY. Rectal cancer level significantly affects rates and patterns of distant metastases among rectal cancer patients post curative-intent surgery without neoadjuvant therapy. World J Surg Oncol. 2014;12:197.

    Article  Google Scholar 

  5. 5.

    Lee JL, Yu CS, Kim TW, Kim JH, Kim JC. Rate of pulmonary metastasis varies with location of rectal cancer in the patients undergoing curative resection. World J Surg. 2015;39:759–68.

    Article  Google Scholar 

  6. 6.

    Arredondo J, Baixauli J, Beorlegui C, Kim JH, Kim JC. Prognosis factors for recurrence in patients with locally advanced rectal cancer preoperatively treated with chemoradiotherapy and adjuvant chemotherapy. Dis Colon Rectum. 2013;56:416–21.

    Article  Google Scholar 

  7. 7.

    Kobayashi H, Mochizuki H, Morita T, Kotake K, Teramoto T, Kameoka S, et al. Timing of relapse and outcome after curative resection for colorectal cancer: a Japanese multicenter study. Dig Surg. 2009;26:249–55.

    Article  Google Scholar 

  8. 8.

    Tan WJ, Tan HJ, Dorajoo SR, Foo FJ, Tang CL, Chew MH. Rectal cancer surveillance—recurrence patterns and survival outcomes from a cohort followed up beyond 10 years. J Gastrointest Cancer. 2018;49:422–8.

    Article  Google Scholar 

  9. 9.

    Schmoll HJ, Van Cutsem E, Stein A, Valentini V, Glimelius B, Haustermans K, et al. ESMO consensus guidelines for management of patients with colon and rectal cancer. A personalized approach to clinical decision making. Ann Oncol. 2012;23(10):2479–516.

    CAS  Article  Google Scholar 

  10. 10.

    Cottet V, Bouvier V, Rollot F, Jooste V, Bedenne L, Faivre J, et al. Incidence and patterns of late recurrences in rectal cancer patients. Ann Surg Oncol. 2015;22:520–7.

    Article  Google Scholar 

  11. 11.

    Sauer R, Becker H, Hohenberger W, Rödel C, Wittekind C, Fietkau R, et al. Preoperative versus postoperative chemoradiotherapy for rectal cancer. N Engl J Med. 2004;351:1731–40.

    CAS  Article  Google Scholar 

  12. 12.

    Tan KK, Lopes Gde L Jr, Sim R. How uncommon are isolated lung metastases in colorectal cancer? A review from database of 754 patients over 4 years. J Gastrointest Surg. 2009;13:642–8.

    Article  Google Scholar 

  13. 13.

    Mitry E, Guiu B, Cosconea S, Jooste V, Faivre J, Bouvier AM. Epidemiology, management and prognosis of colorectal cancer with lung metastases: a 30-year population-based study. Gut. 2010;59:1383–8.

    Article  Google Scholar 

  14. 14.

    Obrand DI, Gordon PH. Incidence and patterns of recurrence following curative resection for colorectal carcinoma. Dis Colon Rectum. 1997;40:15–24.

    CAS  Article  Google Scholar 

  15. 15.

    Cho YB, Chun HK, Yun HR, Lee WS, Yun SH, Lee WY. Clinical and pathologic evaluation of patients with recurrence of colorectal cancer five or more years after curative resection. Dis Colon Rectum. 2007;50:1204–10.

    Article  Google Scholar 

  16. 16.

    Umpleby HC, Bristol JB, Rainey JB, Williamson RC. Survival of 727 patients with single carcinomas of the large bowel. Dis Colon Rectum. 1984;27:803–10.

    CAS  Article  Google Scholar 

  17. 17.

    Sadahiro S, Suzuki T, Ishikawa K, Nakamura T, Tanaka Y, Masuda T, et al. Recurrence patterns after curative resection of colorectal cancer in patients followed for a minimum of ten years. Hepato-Gastroenterology. 2003;50:1362–6.

    PubMed  Google Scholar 

  18. 18.

    Broadbridge VT, Karapetis CS, Beeke C, Woodman RJ, Padbury R, Maddern G, et al. Do metastatic colorectal cancer patients who present with late relapse after curative surgery have a better survival? Br J Cancer. 2013;109(5):1338–43.

    CAS  Article  Google Scholar 

  19. 19.

    Seo SI, Lim SB, Yoon YS, Kim CW, Yu CS, Kim TW, et al. Comparison of recurrence patterns between≤ 5 years and> 5 years after curative operations in colorectal cancer patients. J Surg Oncol. 2013;108:9–13.

    Article  Google Scholar 

  20. 20.

    Watanabe K, Saito N, Sugito M, Ito M, Kobayashi A, Nishizawa Y. Predictive factors for pulmonary metastases after curative resection of rectal cancer without preoperative chemoradiotherapy. Dis Colon Rectum. 2011;54:989–98.

    Article  Google Scholar 

  21. 21.

    Eisenberg B, Decosse JJ, Harford F, Michalek J. Carcinoma of the colon and rectum: the natural history reviewed in 1704 patients. Cancer. 1982;49:1131–4.

    CAS  Article  Google Scholar 

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Correspondence to Y. Bozkaya.

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Bozkaya, Y., Albayrak, İ., Tucer, D. et al. Late-Onset Lung Metastasis in Rectum Cancer Can Be Confused with Primary Lung Cancer; a Case Report and Literature Review. J Gastrointest Canc 50, 1029–1033 (2019).

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