Hepatocellular Cancer: Is Recurrence Inevitable?
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Hepatocellular cancer (HCC) ranks as the sixth common cancer in the world . Yearly, it is estimated that more than 700,000 people are diagnosed with HCC. However, when it comes to mortality, it is the second cause [1, 2]. More than half of the HCC patients are from East Asia and the most prevalent liver disease causing HCC is chronic hepatitis B (HBV) infection there. The other underlying disorders are chronic hepatitis C infection, alcohol abuse, and metabolic syndrome. Tobacco smoking and dietary aflatoxin exposure are additional confounding factors .
Despite advances in medicine, recurrence after HCC treatment are unacceptably high. In the long-term recurrence, free survival is less than 40% after loco-regional treatments . Here, the current literature in recurrence of HCC is reviewed.
Curative Strategies in HCC Treatment and Recurrence
HCC treatment algorithm is not built on a TNM staging system. Barcelona Clinic Liver Cancer (BCLC) staging system in wide use,...
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