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Small Intestinal Lymphoma in a Post-Renal Transplant Patient: A Rare Case with Late Presentation

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References

  1. LaCasce AS. Post-transplant lymphoproliferative disorders. Oncologist. 2006;11(6):674–80.

    Article  PubMed  Google Scholar 

  2. Loren AW, Porter DL, Stadtmauer EA, Tsai DE. Post-transplant lymphoproliferative disorder: a review. Bone Marrow Transplant. 2003;31(3):145–55.

    Article  CAS  PubMed  Google Scholar 

  3. Paya CV, Fung JJ, Nalesnik MA, Kieff E, Green M, Gores G, et al. Epstein–Barr virus-induced posttransplant lymphoproliferative disorders. ASTS/ASTP EBV-PTLD Task Force and The Mayo Clinic Organized International Consensus Development Meeting. Transplantation. 1999;68(10):1517–25.

    Article  CAS  PubMed  Google Scholar 

  4. Schulz TF. Cancer and viral infections in immunocompromised individuals. Int J Cancer. 2009;125(8):1755–63.

    Article  CAS  PubMed  Google Scholar 

  5. Preiksaitis JK, Keay S. Diagnosis and management of posttransplant lymphoproliferative disorder in solid-organ transplant recipients. Clin Infect Dis. 2001;33(1):38–46.

    Article  Google Scholar 

  6. Taylor AL, Marcus R, Bradley JA. Post-transplant lymphoproliferative disorders (PTLD) after solid organ transplantation. Crit Rev Oncol Hematol. 2005;56(1):155–67.

    Article  PubMed  Google Scholar 

  7. Jagadeesh D, Woda BA, Draper J, Evens AM. Post transplant lymphoproliferative disorders: risk, classification, and therapeutic recommendations. Curr Treat Options Oncol. 2012;13(1):122–36.

    Article  PubMed  Google Scholar 

  8. Leblond V, Davi F, Charlotte F, Dorent R, Bitker MO, Sutton L, et al. Posttransplant lymphoproliferative disorders not associated with Epstein–Barr virus: a distinct entity? J Clin Oncol. 1998;16(6):2052–9.

    CAS  PubMed  Google Scholar 

  9. Tsai DE, Hardy CL, Tomaszewski JE, Kotloff RM, Oltoff KM, Somer BG, et al. Reduction in immunosuppression as initial therapy for posttransplant lymphoproliferative disorder: analysis of prognostic variables and long-term follow-up of 42 adult patients. Transplantation. 2001;71(8):1076–88.

    Article  CAS  PubMed  Google Scholar 

  10. Buell JF, Gross TG, Hanaway MJ, Trofe J, Muthiak C, First MR, et al. Chemotherapy for posttransplant lymphoproliferative disorder: the Israel Penn International Transplant Tumor Registry experience. Transplant Proc. 2005;37(2):956–7.

    Article  CAS  PubMed  Google Scholar 

  11. Elstrom RL, Andreadis C, Aqui NA, Ahya VN, Bloom RD, Brozena SC, et al. Treatment of PTLD with rituximab or chemotherapy. Am J Transplant. 2006;6(3):569–76.

    Article  CAS  PubMed  Google Scholar 

  12. Mamzer-Bruneel MF, Lomé C, Morelon E, Levy V, Bourquelot P, Jacobs F, et al. Durable remission after aggressive chemotherapy for very late post-kidney transplant lymphoproliferation: a report of 16 cases observed in a single center. J Clin Oncol. 2000;18(21):3622–32.

    CAS  PubMed  Google Scholar 

  13. Benkerrou M, Jais JP, Leblond V, Durandy A, Sutton L, Bordigoni P, et al. Anti-B-cell monoclonal antibody treatment of severe posttransplant B-lymphoproliferative disorder: prognostic factors and long-term outcome. Blood. 1998;92(9):3137–47.

    CAS  PubMed  Google Scholar 

  14. Choquet S, Leblond V, Herbrecht R, Socié G, Stoppa A-M, Vandenberghe P, et al. Efficacy and safety of rituximab in B-cell post-transplantation lymphoproliferative disorders: results of a prospective multicenter phase 2 study. Blood. 2006;107(8):3053–7.

    Article  CAS  PubMed  Google Scholar 

  15. Choquet S, Oertel S, LeBlond V, Riess H, Varoqueaux N, Dörken B, et al. Rituximab in the management of post-transplantation lymphoproliferative disorder after solid organ transplantation: proceed with caution. Ann Hematol. 2007;86(8):599–607.

    Article  CAS  PubMed  Google Scholar 

  16. Parker A, Bowles K, Bradley JA, Emery V, Featherstone C, Gupte G, et al. Management of post-transplant lymphoproliferative disorder in adult solid organ transplant recipients - BCSH and BTS Guidelines. Br J Haematol. 2010;149(5):693–705.

    Article  PubMed  Google Scholar 

  17. Funch DP, Walker AM, Schneider G, Ziyadeh NJ, Pescovitz MD. Ganciclovir and acyclovir reduce the risk of post-transplant lymphoproliferative disorder in renal transplant recipients. Am J Transplant. 2005;5(12):2894–900.

    Article  CAS  PubMed  Google Scholar 

  18. Green M, Reyes J, Webber S, Rowe D. The role of antiviral and immunoglobulin therapy in the prevention of Epstein–Barr virus infection and post-transplant lymphoproliferative disease following solid organ transplantation. Transpl Infect Dis. 2001;3(2):97–103.

    Article  CAS  PubMed  Google Scholar 

  19. Davis CL, Wood BL, Sabath DE, Joseph JS, Stehman-Breen C, Broudy VC. Interferon-alpha treatment of posttransplant lymphoproliferative disorder in recipients of solid organ transplants. Transplantation. 1998;66(12):1770–9.

    Article  CAS  PubMed  Google Scholar 

  20. Leblond V, Dhedin N, Mamzer Bruneel MF, Choquet S, Hermine O, Porcher R, et al. Identification of prognostic factors in 61 patients with posttransplantation lymphoproliferative disorders. J Clin Oncol. 2001;19(3):772–8.

    CAS  PubMed  Google Scholar 

  21. Choquet S, Mamzer BM-F, Hermine O, Porcher R, Nguyen QS, Davi F, et al. Identification of prognostic factors in post-transplant lymphoproliferative disorders. Recent Results Cancer Res. 2002;159:67–80.

    Article  PubMed  Google Scholar 

  22. Ghobrial IM, Habermann TM, Maurer MJ, Geyer SM, Ristow KM, Larson TS, et al. Prognostic analysis for survival in adult solid organ transplant recipients with post-transplantation lymphoproliferative disorders. J Clin Oncol. 2005;23(30):7574–82.

    Article  PubMed  Google Scholar 

  23. Ghobrial IM, Habermann TM, Ristow KM, Ansell SM, Macon W, Geyer SM, et al. Prognostic factors in patients with post-transplant lymphoproliferative disorders (PTLD) in the rituximab era. Leuk Lymphoma. 2005;46(2):191–6.

    Article  CAS  PubMed  Google Scholar 

  24. Trofe J, Buell JF, Beebe TM, Hanaway MJ, First MR, Alloway RR, et al. Analysis of factors that influence survival with post-transplant lymphoproliferative disorder in renal transplant recipients: the Israel Penn International Transplant Tumor Registry experience. Am J Transplant. 2005;5(4 Pt 1):775–80.

    Article  PubMed  Google Scholar 

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Correspondence to Ritesh Kumar.

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Kumar, R., Khosla, D., Kapoor, R. et al. Small Intestinal Lymphoma in a Post-Renal Transplant Patient: A Rare Case with Late Presentation. J Gastrointest Canc 45 (Suppl 1), 2–5 (2014). https://doi.org/10.1007/s12029-013-9517-3

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