Skip to main content
Log in

Hepato-biliary Cystadenoma with Intraductal Extension: Unusual Cause of Obstructive Jaundice

  • Case Report
  • Published:
Journal of Gastrointestinal Cancer Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5

References

  1. Wheeler DA, Edmondson HA. Cystadenoma with mesenchymal stroma (CMS) in the liver and bile ducts. A clinicopathologic study of 17 cases, 4 with malignant change. Cancer. 1985;56(6):1434–45.

    Article  PubMed  CAS  Google Scholar 

  2. Sutton CD, White SA, Berry DP, Dennison AR. Intrahepatic biliary cystadenoma causing luminal common bile duct obstruction. Dig Surg. 2000;17(3):297–9.

    Article  PubMed  CAS  Google Scholar 

  3. Erdogan D, Kloek J, Lamers WH, Offerhaus GJ, Busch OR, Gouma DJ, et al. Mucinous cystadenomas in liver: management and origin. Dig Surg. 2010;27(1):19–23. Epub 2010 Apr 1.

    Article  PubMed  CAS  Google Scholar 

  4. Yi B, Cheng QB, Jiang XQ, Liu C, Luo XJ, Dong H, et al. A special growth manner of intrahepatic biliary cystadenoma. World J Gastroenterol. 2009;15(48):6134–6.

    Article  PubMed  Google Scholar 

  5. Beuran M, Venter MD, Dumitru L. Large mucinous biliary cystadenoma with "ovarian-like" stroma: a case report. World J Gastroenterol. 2006;12(23):3779–81.

    PubMed  Google Scholar 

  6. Thomas KT, Welch D, Trueblood A, Sulur P, Wise P, Gorden DL, et al. Effective treatment of biliary cystadenoma. Ann Surg. 2005;241(5):769–73. discussion 773–775.

    Article  PubMed  Google Scholar 

  7. Mortelé KJ, Ros PR. Cystic focal liver lesions in the adult: differential CT and MR imaging features. Radiographics. 2001;21(4):895–910.

    PubMed  Google Scholar 

  8. Palacios E, Shannon M, Solomon C, Guzman M. Biliary cystadenoma: ultrasound, CT, and MRI. Gastrointest Radiol. 1990;15(4):313–6.

    Article  PubMed  CAS  Google Scholar 

  9. Marcial MA, Hauser SC, Cibas ES, Braver J. Intrahepatic biliary cystadenoma. Clinical, radiological, and pathological findings. Dig Dis Sci. 1986;31(8):884–8.

    Article  PubMed  CAS  Google Scholar 

  10. Ray S, Khamrui S, Mridha AR, Mukherjee B. Extrahepatic biliary cystadenoma: an unusual cause of recurrent cholangitis. Am J Surg. 2010;199(1):e3–4. Epub 2009 Oct 17.

    Article  PubMed  Google Scholar 

  11. Davies W, Chow M, Nagorney D. Extrahepatic biliary cystadenomas and cystadenocarcinoma. Report of seven cases and review of the literature. Ann Surg. 1995;222(5):619–25. Review.

    Article  PubMed  CAS  Google Scholar 

  12. Akwari OE, Tucker A, Seigler HF, Itani KM. Hepatobiliary cystadenoma with mesenchymal stroma. Ann Surg. 1990;211(1):18–27. Review.

    Article  PubMed  CAS  Google Scholar 

  13. Erdogan D, Busch OR, Rauws EA, van Delden OM, Gouma DJ, van-Gulik TM. Obstructive jaundice due to hepatobiliary cystadenoma or cystadenocarcinoma. World J Gastroenterol. 2006;12(35):5735–8.

    PubMed  Google Scholar 

  14. Gonzalez M, Majno P, Terraz S, Morel P, Rubbia-Brandt L, Mentha G. Biliary cystadenoma revealed by obstructive jaundice. Dig Liver Dis. 2009;41(7):e11–3. Epub 2008 Mar 7.

    Article  PubMed  CAS  Google Scholar 

  15. Ishak KG, Willis GW, Cummins SD, Bullock AA. Biliary cystadenoma and cystadenocarcinoma: report of 14 cases and review of the literature. Cancer. 1977;39(1):322–38. Review.

    Article  PubMed  CAS  Google Scholar 

  16. Sirén J, Kärkkäinen P, Luukkonen P, Kiviluoto T, Kivilaakso E. A case report of biliary cystadenoma and cystadenocarcinoma. Hepatogastroenterology. 1998;45(19):83–9.

    PubMed  Google Scholar 

  17. Frick MP, Feinberg SB. Biliary cystadenoma. AJR Am J Roentgenol. 1982;139(2):393–5.

    PubMed  CAS  Google Scholar 

  18. Florman SS, Slakey DP. Giant biliary cystadenoma: case report and literature review. Am Surg. 2001;67(8):727–32.

    PubMed  CAS  Google Scholar 

  19. Choi BI, Lim JH, Han MC, Lee DH, Kim SH, Kim YI, et al. Biliary cystadenoma and cystadenocarcinoma: CT and sonographic findings. Radiology. 1989;171(1):57–61.

    PubMed  CAS  Google Scholar 

  20. Genkins SM, Tucker JA, Seigler HF, Dunnick NR. Biliary cystadenoma with mesenchymal stroma: CT and angiographic appearance. J Comput Assist Tomogr. 1988;12(3):527–9.

    Article  PubMed  CAS  Google Scholar 

  21. Smith JA, Collier NA, Gibson RN. Biliary obstruction due to intraductal tumor. Aust N Z J Surg. 1989;59(8):625–9.

    Article  PubMed  CAS  Google Scholar 

  22. Forrest ME, Cho KJ, Shields JJ, Wicks JD, Silver TM, McCormick TL. Biliary cystadenomas: sonographic–angiographic–pathologic correlations. AJR Am J Roentgenol. 1980;135(4):723–7.

    PubMed  CAS  Google Scholar 

  23. Federle MP, Filly RA, Moss AA. Cystic hepatic neoplasms: complementary roles of CT and sonography. AJR Am J Roentgenol. 1981;136(2):345–8.

    PubMed  CAS  Google Scholar 

  24. Lewin M, Mourra N, Honigman I, Fléjou JF, Parc R, Arrivé L, et al. Assessment of MRI and MRCP in diagnosis of biliary cystadenoma and cystadenocarcinoma. Eur Radiol. 2006;16(2):407–13. Epub 2005 Jun 28.

    Article  PubMed  Google Scholar 

  25. Seidel R, Weinrich M, Pistorius G, Fries P, Schneider G. Biliary cystadenoma of the left intrahepatic duct (2007: 2b). Eur Radiol. 2007;17(5):1380–3. Epub 2007 Mar 14.

    Article  PubMed  Google Scholar 

  26. Zen Y, Fujii T, Itatsu K, Nakamura K, Konishi F, Masuda S, et al. Biliary cystic tumors with bile duct communication: a cystic variant of intraductal papillary neoplasm of the bile duct. Mod Pathol. 2006;19(9):1243–54. Epub 2006 Jun 2.

    Article  PubMed  Google Scholar 

  27. Stanley J, Vujic I, Schabel SI, Gobien RP, Reines HD. Evaluation of biliary cystadenoma and cystadenocarcinoma. Gastrointest Radiol. 1983;8(3):245–8.

    Article  PubMed  CAS  Google Scholar 

  28. Fiamingo P, Veroux M, Cillo U, Basso S, Buffone A, D'Amico DF. Incidental cystadenoma after laparoscopic treatment of hepatic cysts: which strategy? Surg Laparosc Endosc Percutan Tech. 2004;14(5):282–4.

    Article  PubMed  Google Scholar 

  29. Makino I, Yoshimitsu Y, Sakuma H, Nakai M, Ueda H. A large cystic tumor with bile duct communication originating around the hepatic hilum. J Gastrointestin Liver Dis. 2010;19(1):77–80.

    PubMed  Google Scholar 

  30. Buetow PC, Buck JL, Pantongrag-Brown L, Ros PR, Devaney K, Goodman ZD, et al. Biliary cystadenoma and cystadenocarcinoma: clinical-imaging-pathologic correlations with emphasis on the importance of ovarian stroma. Radiology. 1995;196(3):805–10.

    PubMed  CAS  Google Scholar 

  31. Zen Y, Fujii T, Itatsu K, Nakamura K, Minato H, Kasashima S, et al. Biliary papillary tumors share pathological features with intraductal papillary mucinous neoplasm of the pancreas. Hepatology. 2006;44(5):1333–43.

    Article  PubMed  CAS  Google Scholar 

  32. Zamboni G, Scarpa A, Bogina G, Iacono C, Bassi C, Talamini G, et al. Mucinous cystic tumors of the pancreas: clinicopathological features, prognosis, and relationship to other mucinous cystic tumors. Am J Surg Pathol. 1999;23(4):410–22.

    Article  PubMed  CAS  Google Scholar 

  33. Zhou JP, Dong M, Zhang Y, Kong FM, Guo KJ, Tian YL. Giant mucinous biliary cystadenoma: a case report. Hepatobiliary Pancreat Dis Int. 2007;6(1):101–3.

    PubMed  Google Scholar 

  34. Duncan Jr WL, Barraza MA. Splenogonadal fusion: a case report and review of literature. J Pediatr Surg. 2005;40(12):e5–7. Review.

    Article  PubMed  Google Scholar 

  35. Colombari R, Tsui WM. Biliary tumors of the liver. Semin Liver Dis. 1995;15(4):402–13. Review.

    Article  PubMed  CAS  Google Scholar 

  36. Devaney K, Goodman ZD, Ishak KG. Hepatobiliary cystadenoma and cystadenocarcinoma. A light microscopic and immunohistochemical study of 70 patients. Am J Surg Pathol. 1994;18(11):1078–91.

    Article  PubMed  CAS  Google Scholar 

  37. Gourley WK, Kumar D, Bouton MS, Fish JC, Nealon W. Cystadenoma and cystadenocarcinoma with mesenchymal stroma of the liver. Immunohistochemical analysis. Arch Pathol Lab Med. 1992;116(10):1047–50.

    PubMed  CAS  Google Scholar 

  38. Woods GL. Biliary cystadenocarcinoma: case report of hepatic malignancy originating in benign cystadenoma. Cancer. 1981;47(12):2936–40.

    Article  PubMed  CAS  Google Scholar 

  39. Beretta E, De Franchis R, Staudacher C, Faravelli A, Primignani M, Vecchi M, et al. Biliary cystadenoma: an uncommon cause of recurrent cholestatic jaundice. Am J Gastroenterol. 1986;81(2):138–40.

    PubMed  CAS  Google Scholar 

  40. Baudin G, Novellas S, Buratti MS, Saint-Paul MC, Chevallier P, Gugenheim J, et al. Atypical MRI features of a biliary cystadenoma revealed by jaundice. Clin Imaging. 2006;30(6):413–5.

    Article  PubMed  Google Scholar 

  41. Pinson CW, Munson JL, Rossi RL, Braasch JW. Enucleation of intrahepatic biliary cystadenomas. Surg Gynecol Obstet. 1989;168(6):534–7.

    PubMed  CAS  Google Scholar 

  42. Akiyoshi T, Yamaguchi K, Chijiiwa K, Tanaka M. Cystadenocarcinoma of the liver without mesenchymal stroma: possible progression from a benign cystic lesion suspected by follow-up imagings. J Gastroenterol. 2003;38(6):588–92.

    PubMed  Google Scholar 

  43. Hai S, Hirohashi K, Uenishi T, Yamamoto T, Shuto T, Tanaka H, et al. Surgical management of cystic hepatic neoplasms. J Gastroenterol. 2003;38(8):759–64.

    Article  PubMed  Google Scholar 

  44. Vogt DP, Henderson JM, Chmielewski E. Cystadenoma and cystadenocarcinoma of the liver: a single center experience. J Am Coll Surg. 2005;200(5):727–33.

    Article  PubMed  Google Scholar 

Download references

Acknowledgements

This article and its contents have not been submitted simultaneously to another journal, have not been accepted for publication elsewhere and have not already been published.

SM and SV drafted the manuscript. All authors have significantly contributed to, read and approved the final manuscript. All authors declare that they have no competing interests. There are no conflicts of interest. There are no financial disclosures.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Soumil Vyas.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Vyas, S., Markar, S., Ezzat, T. et al. Hepato-biliary Cystadenoma with Intraductal Extension: Unusual Cause of Obstructive Jaundice. J Gastrointest Canc 43 (Suppl 1), 32–37 (2012). https://doi.org/10.1007/s12029-011-9289-6

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12029-011-9289-6

Keywords

Navigation