Abstract
Introduction
Sclerosing mesenteritis is a rare fibroinflammatory disease of unknown pathogenesis and etiology. Although more commonly benign in its clinical course, sclerosing mesenteritis can mimic certain malignant disorders, such as lymphoma.
Case Report
This report describes the case of a previously healthy young woman who develops an acute illness thought to be related to sclerosing mesenteritis following an extensive diagnostic work-up including biopsy sampling, which was negative for malignancy. However, despite aggressive medical care, the patient passed away. Autopsy revealed extensive inflammation secondary to anaplastic lymphoma.
Conclusion
The case very graphically highlights an important clinical observation that lymphoma can masquerade as sclerosing mesenteritis.
References
Akram S, Pardi DS, Schaffner JA, Smryk TC. Sclerosing mesenteritis: clinical features, treatment, and outcome in ninety-two patients. Clin Gastroenterol Hepatol. 2007;5:589–96.
Emory TS, Monihan JM, Carr NJ, Sobin LH. Sclerosing mesenteritis, mesenteric panniculitis and mesenteric lipodystrophy: a single entity? Am J Surg Pathol. 1997;21:392–8.
Phillips RH, Carr RA, Preston R, Pereira SP, Wilkinson ML, O’Donnell PJ, et al. Sclerosing mesenteritis involving the pancreas: two cases of a rare cause of abdominal mass mimicking malignancy. Eur J Gastroenterol Hepatol. 1999;11:1323–9.
Badiola-Varela CM, Sussman Sk, Glickstein MF. Mesenteric panniculitis: findings on CT, MRI, and angiography. Clin Imaging. 1991;15:265–7.
Sabate JM, Torrubia S, Maideu J, Franquet T, Monill JM, Perez C. Sclerosing mesenteritis: imaging findings in 17 patients. AJR Am J Roentgenol. 1999;172:625–9.
Kipfer RE, Moertel CG, Dahlin DC. Mesenteric lipodystrophy. Ann Intern Med. 1974;80:582–8.
Bechade D, Durand X, Desrame J, Rambelo A, Corberand D, Baranger B, et al. Etiologic spectrum of mesenteric panniculitis: report of 7 cases. Rev Méd Interne. 2007;28:289–95.
Bares R, Klever P, Hauptmann S, Hellwig D, Fass J, Cremerius U, et al. F-18 flurodeoxyglucose PET in vivo evaluation of pancreatic glucose metabolism for detection of pancreatic cancer. Radiology. 1994;192:79–86.
Kubota K, Yamada K, Yoshioka S, Yamada S, Ito M, Ido T. Differential diagnosis of idiopathic fibrosis from malignant lymphadenopathy with PET and F-18 flurodeoxyglucose. Clin Nucl Med. 1992;17:361–3.
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Luther, J., Faje, A.J., Al-Hawary, M. et al. Anaplastic Lymphoma Masquerading as Sclerosing Mesenteritis: A Case Report. J Gastrointest Canc 43, 364–366 (2012). https://doi.org/10.1007/s12029-011-9263-3
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DOI: https://doi.org/10.1007/s12029-011-9263-3