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Hypoglycaemia in a 63-Year-Old Female with a Large, Recurrent, Metastatic Gastrointestinal Stromal Tumour (GIST)

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Abstract

Introduction

Non-islet cell tumour-induced hypoglycaemia (NICTH) is rare, with few cases reported in patients with gastrointestinal stromal tumour (GIST).

Case Report

A 63-year-old Chinese female with known metastatic GIST presents with persistent hypoglycaemia. Investigations revealed a likely diagnosis of NICTH, and she underwent debulking surgery. There was complete resolution of her hypoglycaemia post-operatively

Discussion

NICTH should be considered in patients with GIST and hypoglycaemia. Surgical debulking is recommended as part of the management of NICTH.

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Fig. 1
Fig. 2

Abbreviations

GIST:

Gastrointestintal stromal tumours

NICTH:

Non-islet cell tumour-induced hypoglycaemia

CT:

Computed tomography

TKI:

Tyrosine kinase inhibitors

SD:

Stable disease

LD:

Limited disease progression

GD:

Generalised disease progression

IGF:

Insulin-like growth factor

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Author information

Authors and Affiliations

  1. Department of General Surgery, Singapore General Hospital, Outram Road, Singapore, 169608, Singapore

    Grace Tan

  2. Department of Surgical Oncology, National Cancer Centre, Singapore, Singapore

    Melissa Teo

  3. Department of Medical Oncology, National Cancer Centre, Singapore, Singapore

    Su Pin Choo

Authors
  1. Grace Tan
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  2. Melissa Teo
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  3. Su Pin Choo
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Correspondence to Grace Tan.

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Tan, G., Teo, M. & Choo, S.P. Hypoglycaemia in a 63-Year-Old Female with a Large, Recurrent, Metastatic Gastrointestinal Stromal Tumour (GIST). J Gastrointest Canc 42, 263–265 (2011). https://doi.org/10.1007/s12029-010-9227-z

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  • DOI: https://doi.org/10.1007/s12029-010-9227-z

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