Abstract
Introduction
Gallbladder carcinoma has been associated with various paraneoplastic syndromes. These may be the presenting manifestations that lead the clinician to a diagnosis.
Case Report
We report a case of small cell gallbladder carcinoma complicated by paraneoplastic hyponatremia. The hyponatremia was further exacerbated by platinum-based chemotherapy.
Discussion
There have previously been no reports of paraneoplastic hyponatremia in gallbladder carcinoma. We discuss the management of this problem and also provide a short literature review on the other paraneoplastic syndromes associated with gallbladder carcinoma.
Conclusion
Symptoms and signs of gallbladder cancer may be insidious. Thorough workup is needed if the patient presents with symptoms and signs of a paraneoplastic syndrome.
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Ng, E.S., Venkateswaran, K., Ganpathi, S.I. et al. Small Cell Gallbladder Carcinoma Complicated by Paraneoplastic Hyponatremia: A Case Report and Literature Review. J Gastrointest Canc 41, 264–268 (2010). https://doi.org/10.1007/s12029-010-9151-2
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DOI: https://doi.org/10.1007/s12029-010-9151-2