Abstract
Background
Our objective was to explore whether a brain death determination (BDD) strategy with demonstration hospitals can accelerate the process of BDD in China.
Methods
We proposed the construction standards for the BDD quality control demonstration hospitals (BDDHs). The quality and quantity of BDD cases were then analyzed.
Results
A total of 107 BDDHs were established from 2013 to 2022 covering 29 provinces, autonomous regions, and municipalities under jurisdiction of the central government of the Chinese mainland (except Qinghai and Tibet). A total of 1,948 professional and technical personnel from these 107 BDDHs received training in BDD, 107 quality control personnel were trained in the quality control management of BDD, and 1,293 instruments for electroencephalography, short-latency somatosensory evoked potential recordings, and transcranial Doppler imaging were provided for BDD. A total of 6,735 BDD cases were submitted to the quality control center. Among the nine quality control indicators for BDD in these cases, the implementation rate, completion rate, and coincidence rate of apnea testing increased the most, reaching 99%.
Conclusions
The strategy of constructing BDDHs to promote BDD is feasible and reliable. Ensuring quality and quantity is a fundamental element for the rapid and orderly popularization of BDD in China.
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References
A definition of irreversible coma. Report of the ad hoc committee of the harvard medical school to examine the definition of brain death. JAMA. 1968;205(6):337–40.
President's Commission for the Study of Ethical Problems in Medicine and Biomedical Behavioral Research. Defining Death: A Report on the Medical, Legal and Ethical Issues in the Determination of Death. President's Council on Bioethics; 1981.
Wijdicks EF. Brain death worldwide: accepted fact but no global consensus in diagnostic criteria. Neurology. 2002;58(1):20–5. https://doi.org/10.1212/wnl.58.1.20.
Wahlster S, Wijdicks EF, Patel PV, Greer DM, Hemphill JC 3rd, Carone M, Mateen FJ. Brain death declaration: practices and perceptions worldwide. Neurology. 2015;84(18):1870–9. https://doi.org/10.1212/WNL.0000000000001540.
Brain Injury Evaluation Quality Control Centre of National Health and Family Planning Commission. Criteria and practical guidance for determination of brain death in adults (BQCC version). Chin Med J. 2013;126(24):4786–90.
Brain Injury Evaluation Quality Control Centre of National Health and Family Planning Commission. Criteria and practical guidance for determination of brain death in children (BQCC version). Chin Med J. 2014;127(23):4140–4.
Brain Injury Evaluation Quality Control Center of National Health Commission; Neurocritical Care Committe of the Chinese Society of Neurology (NCC/CSN); Neurocritical Care Committe of China Neurologist Association (NCC/CNA). Criteria and practical guidance for determination of brain death in adults (2nd edition). Chin Med J. 2019;132(3):329–335. https://doi.org/10.1097/CM9.0000000000000014.
Brain Injury Evaluation Quality Control Center of National Health Commission. Criteria and practical guidance for determination of brain death in children. Zhonghua Er Ke Za Zhi. 2019;57(5):331–5. https://doi.org/10.3760/cma.j.issn.0578-1310.2019.05.003.
Su Y, Yang Q, Liu G, Zhang Y, Ye H, Gao D, Zhang Y, Chen W. Diagnosis of brain death: confirmatory tests after clinical test. Chin Med J. 2014;127(7):1272–7.
Su YY, Chen WB, Liu G, Fan LL, Zhang Y, Ye H, Gao DQ, Liu YF, Jiang MD. An investigation and suggestions for the improvement of brain death determination in China. Chin Med J. 2018;131(24):2910–4. https://doi.org/10.4103/0366-6999.247193.
Su Y, Zhang Y, Chen W, Tian F, Fan L, Liu G, Huang H, Zhang Y, Wang J, Deng Y. Minimum criteria for brain death determination: consensus promotion and Chinese practice. Neurocrit Care. 2022;37(2):479–86. https://doi.org/10.1007/s12028-022-01508-0.
Sayan HE. Retrospective analysis of the apnea test and ancillary test in determining brain death. Rev Bras Ter Intensiva. 2020;32(3):405–11.
Wijdicks EF, Rabinstein AA, Manno EM, Atkinson JD. Pronouncing brain death: contemporary practice and safety of the apnea test. Neurology. 2008;71:1240–4.
Chen Z, Su Y, Liu G, Fan L, Zhang Y, Chen W, Ye H, Huang H. Investigation of Apnea Testing During Brain Death Determination in China. ASAIO J. 2021;67(11):1211–6.
Greer DM, Shemie SD, Lewis A, et al. Determination of brain death/death by neurologic criteria: the world brain death project. JAMA. 2020;324(11):1078–97.
2019 China Health Statistics Yearbook.
Neurocritical Care Society. Brain death toolkit. Accessed July 16, 2020. https://www.neurocriticalcare.org/education/digital-education/brain-death-toolki
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Conception and design of the study: YS. Acquisition of data: YZ, WC, FT, LF, GL, HH, CG, YS. Analysis and interpretation of data: YS, HH, CG, YS, YH. Drafting of the article or critical revision for important intellectual content: YS, WC, HH, YZ, FT, LF, GL, CG, YS, YH, HC. All authors approved the final manuscript.
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Su, Y., Chen, W., Zhang, Y. et al. To Accelerate the Process of Brain Death Determination in China Through the Strategy and Practice of Establishing Demonstration Hospitals. Neurocrit Care (2024). https://doi.org/10.1007/s12028-023-01908-w
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DOI: https://doi.org/10.1007/s12028-023-01908-w