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10 or 15 or 20 or 40 mmHg? What is Increased Intracranial Pressure and Who Said So?

  • Neurocritial Care Through History
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  1. Williams B. Cerebrospinal fluid pressure changes in response to coughing. Brain. 1976;99:331–46.

    Article  CAS  Google Scholar 

  2. Langfitt TW, Weinstein JD, Kassell NF. Cerebral vasomotor paralysis produced by intracranial hypertension. Neurology. 1965;15:622–41.

    Article  CAS  Google Scholar 

  3. Sullivan HG, Miller JD, Becker DP, Flora RE, Allen GA. The physiological basis of intracranial pressure change with progressive epidural brain compression. An experimental evaluation in cats. J Neurosurg. 1977;47:532–50.

    Article  CAS  Google Scholar 

  4. Lundberg N, Troupp H, Lorin H. Continuous recording of the ventricular-fluid pressure in patients with severe acute traumatic brain injury. A preliminary report. J Neurosurg. 1965;22:581–90.

    Article  CAS  Google Scholar 

  5. Wijdicks EFM. Lundberg and his waves. Neurocrit Care. 2019;31:546–9.

    Article  Google Scholar 

  6. Miller JD, Becker DP, Ward JD, Sullivan HG, Adams WE, Rosner MJ. Significance of intracranial hypertension in severe head injury. J Neurosurg. 1977;47:503–16.

    Article  CAS  Google Scholar 

  7. Miller JD, Pickard JD. Intracranial volume pressure studies in patients with head injury. Injury. 1974;5:265–8.

    Article  CAS  Google Scholar 

  8. Bruce DA, Langfitt TW, Miller JD, et al. Regional cerebral blood flow, intracranial pressure, and brain metabolism in comatose patients. J Neurosurg. 1973;38:131–44.

    Article  CAS  Google Scholar 

  9. Marshall LF, Graham DI, Durity F, Lounsbury R, Langfitt TW. Effects of severe experimental intracranial hypertension on the rabbit brain. Surg Forum. 1974;25:456–8.

    CAS  PubMed  Google Scholar 

  10. Enevoldsen EM, Cold G, Jensen FT, Malmros R. Dynamic changes in regional CBF, intraventricular pressure, CSF pH and lactate levels during the acute phase of head injury. J Neurosurg. 1976;44:191–214.

    Article  CAS  Google Scholar 

  11. Le Roux P, Menon DK, Citerio G, et al. Consensus summary statement of the International Multidisciplinary Consensus Conference on Multimodality Monitoring in Neurocritical Care: a statement for healthcare professionals from the Neurocritical Care Society and the European Society of Intensive Care Medicine. Intensive Care Med. 2014;40:1189–209.

    Article  Google Scholar 

  12. Guiza F, Depreitere B, Piper I, et al. Visualizing the pressure and time burden of intracranial hypertension in adult and paediatric traumatic brain injury. Intensive Care Med. 2015;41:1067–76.

    Article  Google Scholar 

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Authorship requirements have been met—Dr. Wijdicks is sole author. The author approves of the final manuscript.

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Correspondence to Eelco F. M. Wijdicks.

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Wijdicks, E.F.M. 10 or 15 or 20 or 40 mmHg? What is Increased Intracranial Pressure and Who Said So?. Neurocrit Care 36, 1022–1026 (2022).

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