Neurocritical Care

, Volume 31, Issue 2, pp 423–427 | Cite as

A Case of HIV Seroconversion Presenting Similarly to Anti-N-methyl-d-aspartate Receptor Encephalitis

  • Heather VanDongen-Trimmer
  • Kumar Sannagowdara
  • Binod Balakrishnan
  • Raquel Farias-MoellerEmail author
A Day in the Life of a Neurocritical Care Trainee


Continuous electroencephalogram (cEEG) monitoring is recommended in patients with acute supratentorial brain injury and altered mental status, such as patients with encephalitis. This practice may help facilitate prompt treatment of non-convulsive seizures and status epilepticus as well as assess the severity of encephalopathy [1]. As more critically ill patients with encephalopathy are being monitored with cEEG, experience is gained in recognizing EEG background patterns that can aid in prognostication, prediction of illness trajectory, and in a few occasions as biomarkers for specific disease processes [1].

Patients with N-methyl-d-aspartate receptor encephalitis (NMDARE) usually present with amnesia, seizures, psychiatric symptoms, dyskinesias, and autonomic dysfunction. Since the discovery of this antibody-mediated encephalitis in 2005 [2, 3], significant advances have been made in the description of the pathophysiology, clinical presentation, biomarkers, and...


Author’s Contributions

Heather VanDongen-Trimmer was involved in data collection, manuscript redaction and editing, original conceptualization of the manuscript. Binod Balakrishnan was involved in data collection, manuscript redaction and editing. Kumar Sannagowdara was involved in data collection, image identification, review and editing, manuscript redaction and editing. Raquel Farias-Moeller was involved in data collection, manuscript redaction and editing, original conceptualization of the manuscript, project supervision.

Source of Support

No external funding was received for this manuscript.

Conflict of interest

The authors have no potential conflicts of interest to disclose.

Ethical approval/Informed consent

Ethical approval was obtained by our institutional review board prior to submission and the case is devoid of personal identifying information.


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature and Neurocritical Care Society 2019

Authors and Affiliations

  1. 1.Division of Child Neurology, Department of NeurologyChildren’s Hospital of Wisconsin, Medical College of WisconsinMilwaukeeUSA
  2. 2.Division of Pediatric Critical Care Medicine, Department of PediatricsChildren’s Hospital of Wisconsin, Medical College of WisconsinMilwaukeeUSA

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