Neurocritical Care

, Volume 18, Issue 1, pp 118–130 | Cite as

Influenza-Associated Neurological Complications

Review Article


While mostly diagnosed in the pediatric population, neurological complications of pandemic influenza A infection may affect young and previously healthy adults, and may follow a fulminant, severe, and occasionally fatal course. We reviewed severe neurological complications secondary to influenza infection reported in the literature, in attempt to outline recurrent syndromes that may assist the clinician in making a timely diagnosis. Vigilance and awareness of these clinical entities are key in the neurologist and intensivist’s role in surveillance and early recognition of pandemic influenza, and in ensuring improved survival for affected patients.


Influenza Influenza vaccine Encephalopathy Brain edema H1N1 Coma 


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© Springer Science+Business Media New York 2012

Authors and Affiliations

  1. 1.Department of Medicine, Division of NeurologyUniversity of TorontoTorontoCanada
  2. 2.Departments of Critical Care and Anesthesia, St. Michael’s HospitalUniversity of TorontoTorontoCanada
  3. 3.Department of Anesthesia and Inter-Departmental Division of Critical CareUniversity of TorontoTorontoCanada

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