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Listeria monocytogenes Meningitis Associated with Rhabdomyolysis and Acute Renal Failure

Abstract

Introduction

Numerous systemic infections are capable of inducing myositis and rhabdomyolysis. Clinical course of the disease is in the great majority of patients benign and without development of renal dysfunction. However, serious consequences are possible if acute renal failure (ARF) occurs, especially in critically ill patients.

Methods

Patient with Listeria monocytogenes meningitis associated with rhabdomyolysis and acute non-oliguric ARF is presented.

Results

Sixty-nine-year-old white male was admitted to our intensive care unit because of listerial meningitis. The course of the disease was complicated with rhabdomyolysis and non-oliguric ARF. After antimicrobial treatment with parenteral trimethoprim-sulfamethoxazole and 4 days of continuous veno-venous hemodiafiltration (CVVHDF) the patient recovered.

Conclusion

We report a case of listerial meningitis complicated with non-oliguric ARF. Rhabdomyolysis should be considered in all patients with infection and increased CK, especially if consciousness is impaired is altered. Furthermore, despite the normal diuresis ARF could be present and result in adverse consequences. We infer that timely diagnosis and treatment should improve the outcome of infection-induced rhabdomyolysis and could prevent a proportion of associated ARF.

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Acknowledgment

We thank Mrs. Arijana Pavelić for her help in the preparation of this manuscript.

Financial disclosure

Supported by the grant from the Croatian Ministry of Science, Education and Sports: No. 108-1080002-0102.

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Correspondence to Marko Kutleša.

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Kutleša, M., Lepur, D., Bukovski, S. et al. Listeria monocytogenes Meningitis Associated with Rhabdomyolysis and Acute Renal Failure. Neurocrit Care 10, 70–72 (2009). https://doi.org/10.1007/s12028-008-9114-7

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Keywords

  • Listeria monocytogenes
  • Rhabdomyolysis
  • Meningitis
  • Creatine kinase
  • Acute renal failure