EPBscore: a Novel Method for Computer-Assisted Analysis of Axonal Structure and Dynamics

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Acknowledgments

We thank Karel Svoboda for support and for critical input on the initial development of EPBscore. Anthony Holtmaat, Linda Wilbrecht for help with an initial set of experiments. Lucien West, Jonathan Bowen, Dawn Thompson, Graham Little for help with the analysis. Cher Bachar for help with Matlab implementation. SS is supported by grants from NSFC (91332122 and 31171047), and a seed grant from the Center for Brain-inspired Computation Research. This work was funded by the Medical Research Council, UK.

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Correspondence to S. Song or V. De Paola.

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S. Song and F. W. Grillo contributed equally to this work.

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Song, S., Grillo, F.W., Xi, J. et al. EPBscore: a Novel Method for Computer-Assisted Analysis of Axonal Structure and Dynamics. Neuroinform 14, 121–127 (2016). https://doi.org/10.1007/s12021-015-9274-5

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Keywords

  • Axons
  • Axonal boutons
  • Automated analysis
  • Segmentation
  • Synaptic plasticity
  • Learning and memory
  • Aging
  • Presynaptic
  • Connectivity
  • In vivo 2-photon imaging