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Antineoplastic activity of artemisinin in adrenocortical carcinoma

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References

  1. Y. Zhang, G. Xu, S. Zhang, D. Wang, P. Saravana Prabha, Z. Zuo, Antitumor research on artemisinin and its bioactive derivatives. Nat. Prod. Bioprospect. 8(4), 303–319 (2018)

    Article  Google Scholar 

  2. Z. Li, Q. Li, J. Wu, M. Wang, J. Yu, Artemisinin and its derivatives as a repurposing anticancer agent: what else do we need to do? Molecules 21(10), 1331 (2016)

    Article  Google Scholar 

  3. T. Efferth, E. Koch, Complex interactions between phytochemicals. The multi-target therapeutic concept of phytotherapy. Curr. Drug Target 12(1), 122–132 (2011)

    Article  CAS  Google Scholar 

  4. L.A. Panossian, N.I. Garga, D. Pelletier, Toxic brainstem encephalopathy after artemisinin treatment for breast cancer. Ann. Neurol. 58(5), 812–813 (2005)

    Article  Google Scholar 

  5. L. Liu, L.F. Zuo, J.W. Guo, Reversal of multidrug resistance by the anti-malaria drug artesunate in the esophageal cancer Eca109/ABCG2 cell line. Oncol. Lett. 6(5), 1475–1481 (2013)

    Article  CAS  Google Scholar 

  6. J.-L. Zhang, Z. Wang, W. Hu, S.-S. Chen, X.-E. Lou, H.-J. Zhou, DHA regulates angiogenesis and improves the efficiency of CDDP for the treatment of lung carcinoma. Microvasc. Res. 87, 14–24 (2013)

    Article  CAS  Google Scholar 

  7. S.-J. Wang, Y. Gao, H. Chen, R. Kong, H.-C. Jiang, S.-H. Pan et al. Dihydroartemisinin inactivates NF-κB and potentiates the anti-tumor effect of gemcitabine on pancreatic cancer both in vitro and in vivo. Cancer Lett. 293(1), 99–108 (2010)

    Article  CAS  Google Scholar 

  8. T. Efferth, Cancer combination therapies with artemisinin-type drugs. Biochemical Pharmacol. 139, 56–70 (2017)

    Article  CAS  Google Scholar 

  9. R. Libé, I. Borget, C.L. Ronchi, B. Zaggia, M. Kroiss, T. Kerkhofs et al. Prognostic factors in stage III–IV adrenocortical carcinomas (ACC): an European Network for the Study of Adrenal Tumor (ENSAT) study. Ann. Oncol. 26(10), 2119–2125 (2015)

    Article  Google Scholar 

  10. A. Berruti, R. Libè, M. Laganà, H. Ettaieb, M.A. Sukkari, J. Bertherat et al. Morbidity and mortality of bone metastases in advanced adrenocortical carcinoma: a multicenter retrospective study. Eur. J. Endocrinol. 180(5), 311–320 (2019)

    Article  CAS  Google Scholar 

  11. M. Fassnacht, O.M. Dekkers, T. Else, E. Baudin, A. Berruti, R.R. de Krijger et al. European Society of Endocrinology Clinical Practice Guidelines on the management of adrenocortical carcinoma in adults, in collaboration with the European Network for the Study of Adrenal Tumors. Eur. J. Endocrinol. 179(4), G1–G46 (2018)

    Article  CAS  Google Scholar 

  12. L. Ferrari, M. Claps, S. Grisanti, A. Berruti, Systemic therapy in locally advanced or metastatic adrenal cancers: a critical appraisal and clinical trial update. Eur. Urol. Focus. 1(3), 298–300 (2016)

    Article  Google Scholar 

  13. P. Sperone, A. Ferrero, F. Daffara, A. Priola, B. Zaggia, M. Volante et al. Gemcitabine plus metronomic 5-fluorouracil or capecitabine as a second-/third-line chemotherapy in advanced adrenocortical carcinoma: a multicenter phase II study. Endocr. Relat. Cancer 17(2), 445–453 (2010)

    Article  CAS  Google Scholar 

  14. J.E.K. Henning, T. Deutschbein, B. Altieri, S. Steinhauer, S. Kircher, S. Sbiera et al. Gemcitabine-based chemotherapy in adrenocortical carcinoma: a multicenter study of efficacy and predictive factors. J. Clin. Endocrinol. Metab. 102(11), 4323–4332 (2017)

    Article  Google Scholar 

  15. M. Terzolo, F. Daffara, A. Ardito, B. Zaggia, V. Basile, L. Ferrari et al. Management of adrenal cancer: a 2013 update. J. Endocrinol. Investig. 37(3), 207–217 (2014)

    Article  CAS  Google Scholar 

  16. D. Cosentini, S. Grisanti, V.A. Dalla, M. Laganà, C. Fiorentini, P. Perotti et al. Immunotherapy failure in adrenocortical cancer: where next? Endocr. Connect. 7(12), E5–E8 (2018)

  17. G. Assié, E. Letouzé, M. Fassnacht, A. Jouinot, W. Luscap, O. Barreau et al. Integrated genomic characterization of adrenocortical carcinoma. Nat. Genet. 46(6), 607–612 (2014)

    Article  Google Scholar 

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Correspondence to Alfredo Berruti.

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This study was supported with the contribution of FIRM Foundation (Cremona, Italy).

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Informed consent was obtained from the patient included in the study.

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Lorini, L., Grisanti, S., Ambrosini, R. et al. Antineoplastic activity of artemisinin in adrenocortical carcinoma. Endocrine 66, 425–427 (2019). https://doi.org/10.1007/s12020-019-02077-7

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  • DOI: https://doi.org/10.1007/s12020-019-02077-7

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