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Risk factors for local recurrence following lateral neck dissection for papillary thyroid carcinoma

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Abstract

Purpose

We aimed to evaluate risk factors for local recurrence following lateral neck dissection (LND) for papillary thyroid carcinoma (PTC).

Methods

Two hundred and nine patients who underwent therapeutic primary or reoperative LND for PTC were included.

Results

One hundred eighty-one patients underwent primary LND at our Institution, the remaining 28 were referred for recurrence following LND outside the Institution. Comparing patients who required reoperation for recurrent lateral neck disease with those who did not recur, no significant difference was found concerning sex, tumor size, multifocal disease, extracapsular invasion, histological variant, pT stage (P = NS). At univariate analysis, age, mean number of removed lateral neck nodes at first operation, the extent of initial LND and surgery performed outside the Institution were risk factors for recurrence (P < 0.001).

Conclusions

Limited LND and surgery performed at non referral Centers were non tumor-related risk factors for recurrence following therapeutic LND for PTC.

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Author notes

  1. This paper is partially based on a work that has been selected as oral presentation at the 7th Biennial Scientific Meeting of European Society of Endocrine Surgeons, 19th–21st May 2016, Istanbul (Turkey).

Authors and Affiliations

  1. Division of Endocrine and Metabolic Surgery, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy

    Marco Raffaelli, Carmela De Crea, Amanda Belluzzi, Celestino P. Lombardi & Rocco Bellantone

  2. Università Cattolica del Sacro Cuore, Rome, Italy

    Marco Raffaelli, Carmela De Crea, Luca Sessa, Serena Elisa Tempera, Celestino P. Lombardi & Rocco Bellantone

Authors
  1. Marco Raffaelli
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  2. Carmela De Crea
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  3. Luca Sessa
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  4. Serena Elisa Tempera
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  5. Amanda Belluzzi
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  6. Celestino P. Lombardi
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  7. Rocco Bellantone
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Correspondence to Carmela De Crea.

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The authors declare that they have no conflict of interest

Ethical standards

All procedures performed in this study were in accordance with ethical standards of the institutional and national research committee and with the 1964 Helsinki declaration and its later amendments.

Informed consent

Informed consent was obtained from all individual participants included in the study.

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Raffaelli, M., De Crea, C., Sessa, L. et al. Risk factors for local recurrence following lateral neck dissection for papillary thyroid carcinoma. Endocrine 63, 310–315 (2019). https://doi.org/10.1007/s12020-018-1788-9

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  • DOI: https://doi.org/10.1007/s12020-018-1788-9

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