Skip to main content
Log in

Pseudodyslipidemia: are we over-treating dyslipidemia in diabetic patients with undiagnosed gastroparesis?

  • Viewpoint
  • Published:
Endocrine Aims and scope Submit manuscript

Abstract

Management of dyslipidemia in diabetic patients poses a major burden on both patients and healthcare providers. Gastroparesis, a condition in which gastric emptying is delayed, is a common condition in diabetes. Given the fact that normal values of plasma lipids are standardized to be measured after several hours of fasting, delayed transit of food and nutrients into the small bowel (as occurs in gastroparesis) may result in an artificial increase in plasma lipids, causing misdiagnosis of dyslipidemia (pseudodyslipidemia), and lead to overtreatment with lipid-lowering agents.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. P.K. Nigam, Serum lipid profile: fasting or non-fasting? Indian J. Clin. Biochem. 26(1), 96–97 (2011)

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  2. W. Xie et al., A new tactic to treat postprandial hyperlipidemia in diabetic rats with gastroparesis by improving gastrointestinal transit. Eur. J. Pharmacol. 510(1–2), 113–120 (2005)

    Article  CAS  PubMed  Google Scholar 

  3. S.B. Harris et al., Glycemic control and morbidity in the Canadian primary care setting (results of the diabetes in Canada evaluation study). Diabetes Res. Clin. Pract. 70(1), 90–97 (2005)

    Article  PubMed  Google Scholar 

  4. M.P. Solano, R.B. Goldberg, Management of dyslipidemia in diabetes. Cardiol. Rev. 14(3), 125–135 (2006)

    Article  PubMed  Google Scholar 

  5. M. Horowitz et al., Gastric emptying in diabetes: clinical significance and treatment. Diabet. Med. 19(3), 177–194 (2002)

    Article  CAS  PubMed  Google Scholar 

  6. J.H. Kim et al., Diabetic factors associated with gastrointestinal symptoms in patients with type 2 diabetes. World J. Gastroenterol. 16(14), 1782–1787 (2010)

    Article  CAS  Google Scholar 

  7. M. Brandle et al., Cost effectiveness of statin therapy for the primary prevention of major coronary events in individuals with type 2 diabetes. Diabetes Care 26(6), 1796–1801 (2003)

    Article  CAS  PubMed  Google Scholar 

  8. R. Kirby, P. Amoroso, M. Kirby, More pro-activity is required in the battle against obesity in men. BJU Int. 103(8), 1019–1020 (2009)

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Tomer Adar.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Adar, T., Lysy, J. Pseudodyslipidemia: are we over-treating dyslipidemia in diabetic patients with undiagnosed gastroparesis?. Endocrine 45, 26–27 (2014). https://doi.org/10.1007/s12020-013-0064-2

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12020-013-0064-2

Keywords

Navigation