Extrapituitary production of anterior pituitary hormones: an overview

Abstract

Protein hormones from the anterior pituitary gland have well-established endocrine roles in their peripheral target glands. It is, however, now known that these proteins are also produced within many of their target tissues, in which they act as local autocrine or paracrine factors, with physiological and/or pathophysiological significance. This emerging concept is the focus of this brief review.

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Acknowledgment

This work was supported by the Natural Science and Research Council of Canada.

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Harvey, S., Arámburo, C. & Sanders, E.J. Extrapituitary production of anterior pituitary hormones: an overview. Endocrine 41, 19–30 (2012). https://doi.org/10.1007/s12020-011-9557-z

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Keywords

  • Growth hormone
  • Prolactin
  • Adrenocorticotropin
  • Thyrotropin
  • Luteinizing hormone
  • Follicle-stimulating hormone