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Improvement in renal dysfunction and symptoms after laparoscopic adrenalectomy in a patient with pheochromocytoma complicated by renal dysfunction

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Abstract

A 70-year-old patient who was undergoing treatment for diabetes mellitus and chronic hepatitis was admitted to our hospital for evaluation of a tumor in the left adrenal gland (50 × 45 mm) and renal failure. On the basis of the patient’s increased serum concentrations of catecholamines and other metabolites and the results of positron emission tomography (PET), the patient was diagnosed with a pheochromocytoma; iodinated metaiodobenzylguanidine ([131I]MIBG) scintigraphy was insufficient to establish this diagnosis. Subsequently, he underwent surgery for tumor resection. Histological examination suggested the tumor to be a malignant pheochromocytoma. After left adrenalectomy was performed, the elevated catecholamine and metabolite concentrations and the blood pressure were restored to normal, and the patient’s symptoms of severe headaches and vertigo reduced. Furthermore, his renal function improved (Cr 2.0–1.2 mg/dl). Our patient exhibited a rare condition of pheochromocytoma complicated by renal failure, which was successfully treated with laparoscopic surgery.

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Authors and Affiliations

  1. Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa, 761-0793, Japan

    Mako Fujiwara, Hitomi Imachi, Koji Murao, Tomie Muraoka, Tomoyo Ohyama & Toshihiko Ishida

  2. Department of Diagnostic Pathology, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa, 761-0793, Japan

    Yumi Miyai, Yoshio Kushida & Reiji Haba

  3. Department of Urology, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa, 761-0793, Japan

    Yoshiyuki Kakehi

Authors
  1. Mako Fujiwara
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  2. Hitomi Imachi
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  3. Koji Murao
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  4. Tomie Muraoka
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  5. Tomoyo Ohyama
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  6. Yumi Miyai
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  7. Yoshio Kushida
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  8. Reiji Haba
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  9. Yoshiyuki Kakehi
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  10. Toshihiko Ishida
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Corresponding author

Correspondence to Hitomi Imachi.

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Fujiwara, M., Imachi, H., Murao, K. et al. Improvement in renal dysfunction and symptoms after laparoscopic adrenalectomy in a patient with pheochromocytoma complicated by renal dysfunction. Endocr 35, 57–62 (2009). https://doi.org/10.1007/s12020-008-9119-1

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  • DOI: https://doi.org/10.1007/s12020-008-9119-1

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