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Vitamin D and diabetes mellitus

Endocrine volume 35, pages 11–17 (2009)Cite this article

Abstract

Better understanding of the physiological role of the vitamin-D system, in particular its potential effects on inflammatory and autoimmune conditions as well as on insulin secretion and possibly also on insulin resistance, increased the interest in its potential role in prevention and control of the diabetic condition, both type-1 and -2 diabetes. Both these conditions are associated with inflammation and type-1 diabetes also with an autoimmune pathology. Indeed, animal and human studies support the notion that adequate vitamin-D supplementation may decrease the incidence of type-1 and possibly also of type-2 diabetes mellitus and may improve the metabolic control in the diabetes state. However, the exact mechanisms by which vitamin-D and calcium supplementation exert their beneficial effects are not clear and need further investigation.

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Acknowledgment

We acknowledge the assistence of the VAMC Detroit MI in preparing this manuscript.

Author information

Authors and Affiliations

  1. Department of Internal Medicine, St. Joseph Mercy Oakland Hospital, Pontiac, MI, USA

    Liviu G. Danescu

  2. Division of Endocrinology, Henry-Ford Hospital, Detroit, MI, USA

    Shiri Levy

  3. Division of Endocrinology VA Medical Center, Wayne State University School of Medicine, 4646 John R, Detroit, MI, 48321, USA

    Joseph Levy

Authors
  1. Liviu G. Danescu
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  2. Shiri Levy
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  3. Joseph Levy
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Correspondence to Joseph Levy.

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Danescu, L.G., Levy, S. & Levy, J. Vitamin D and diabetes mellitus. Endocr 35, 11–17 (2009). https://doi.org/10.1007/s12020-008-9115-5

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  • DOI: https://doi.org/10.1007/s12020-008-9115-5

Keywords

  • Type-1 diabetes
  • Type-2 diabetes
  • Calcium
  • Vitamin-D
  • PTH