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Aortic Stenosis

Comprehensive Therapy volume 33, pages 174–183 (2007)Cite this article

Patients with aortic stenosis (AS) have an increased prevalence of coronary risk factors, coronary artery disease, and other atherosclerotic vascular disease and an increased incidence of coronary events and death. Statins may reduce the progression of AS. Angina pectoris, syncope or near syncope, and heart failure are the three classic manifestations of severe AS. Prolonged duration and late peaking of an aortic systolic ejection murmur best differentiate severe AS from mild AS on physical examination. Doppler echocardiography is used to diagnose the presence and severity of AS. Once symptoms develop, aortic valve replacement (AVR) should be performed in patients with severe or moderate AS. Warfarin should be administered indefinitely after AVR in patients with a mechanical aortic valve and in patients with a bioprosthetic aortic valve who have either atrial fibrillation, prior thromboembolism, left ventricular systolic dysfunction, or a hypercoagulable condition. Patients with a bioprosthetic aortic valve without any of these four risk factors should be treated with aspirin 75–100 mg daily.

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  1. Depatment of Medicine, Divisions of Cardiology, Geriatrics, and Pulmonary/Critical Care, New York Medical College, Macy Pavilion, Room 138, Valhalla, NY, 10595, USA

    Wilbert S. Aronow

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  1. Wilbert S. Aronow
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Correspondence to Wilbert S. Aronow.

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Dr. Aronow has no real or apparent conflicts of interest relating to the subject under discussion.

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Aronow, W.S. Aortic Stenosis. Compr Ther 33, 174–183 (2007). https://doi.org/10.1007/s12019-007-8021-8

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Keywords

  • Left Ventricle
  • Aortic Valve
  • Aortic Stenosis
  • Aortic Valve Replacement
  • Doppler Echocardiography