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As if the cancer wasn't enough! Understanding and treating the pain that comes with cancer

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Comprehensive Therapy

Abstract

In people with cancer, pain often occurs from the malignancy, from procedures done to diagnose, stage, and treat the malignancy, and from the toxicities of therapy used in treating the cancer. Of people with cancer, 75% complain of some sort of pain. Determining whether the pain is from tissue damage or nerve structures will guide therapy. Assessment of the severity of the pain by location, oncological type, as well as psychosocial and environmental factors are necessary to understand and treat the pain that accompanies cancer. Medical interventions include non-opioid analgesics opioids, and multiple different combinations of medications. Adjuvant medication like anticonvulsants and steroids are being used frequently to help people feel more comfortable.

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References

  1. McGuire DB. Occurrence of cancer pain. J Natl Cancer Inst Monogr 2004;32:51–56.

    Article  Google Scholar 

  2. Goudas LC, Bloch R, Gialeli-Goudas M, Lau J, Carr DB. The epidemiology of cancer pain. Cancer Invest 2005;23(2)182–190.

    Article  PubMed  Google Scholar 

  3. Caraceni A, Weinstein SM. Classification of cancer pain syndromes. Oncology 2001;15(12):1627–1640.

    CAS  PubMed  Google Scholar 

  4. Portenoy RK, Lesage P. Management of cancer pain. Lancet 1999;353:1695–1700.

    Article  CAS  PubMed  Google Scholar 

  5. Bruera E, Kim HN. Cancer pain. JAMA 2003;4(5):2476–2479.

    Article  Google Scholar 

  6. Grossman SA, Nesbit S. Cancer pain. In: Clinical Oncology, 3rd ed. (Abeloff MD, Armitage JO, Niederhuber JE, Kastan MB, McKenna WG, eds.) Churchill Livingstone, Philadelphia, 2004, pp. 715–730.

    Google Scholar 

  7. Zech DFJ, Grond S, Lynch J, Hertel D, Lehmann KA. Validation of World Health Organization Guidelines for cancer pain relief: a 10-year prospective study. Pain 1995;63:65–76.

    Article  CAS  PubMed  Google Scholar 

  8. National Comprehensive Cancer Network. Adult cancer pain. In: Practice Guidelines in Oncology, vol. 2, 2005.

  9. WHO. Cancer Pain Relief and Palliative Care. World Health Organization, Geneva, 1996.

    Google Scholar 

  10. Meuser T, Pietruck C, Radbruch, L, Stute P, Lehmann KA, Grond S. Symptoms during cancer pain treatment following WHO-guidelines: a longitudinal follow-up study of symptom prevalence, severity and etiology. Pain 2001;93:247–257.

    Article  CAS  PubMed  Google Scholar 

  11. McNicol E, Strassels SA, Goudas L, Lau J, Carr DB. NSAIDs or paracetamol, alone or combined with opioids, for cancer pain. The Cochrane Database of Systematic Reviews 2005;2.

  12. Cherny NI. The pharmacologic management of cancer pain. Oncology 2004;18(12):1499–1515.

    PubMed  Google Scholar 

  13. McQuay H. Opioids in pain management. Lancet 1999;353: 2229–2232.

    Article  CAS  PubMed  Google Scholar 

  14. Sussman G, Shurman J, Creed MR, et al. Intravenous ondansetron for the control of opioid-induced nausea and vomiting. International S3AA3013 Study Group. Clin Ther 1999;21(7):1216–1227.

    Article  CAS  PubMed  Google Scholar 

  15. Lussier D, Huskey AG, Portenoy RK. Adjuvant analgesics in cancer pain management. Oncologist 2004;9(5):571–591.

    Article  CAS  PubMed  Google Scholar 

  16. Caraceni A, Zecca E, Bonezzi C, et al. Gabapentin for neuropathic cancer pain: a randomized controlled trial from the Gabapentin Cancer Pain Study Group. J Clin Oncol 2004;22(14):2909–2917.

    Article  CAS  PubMed  Google Scholar 

  17. De Pinto M, Dunbar PJ, Edwards WT. Pain management. Anesthesiol Clin North America 2006;24(1):19–37.

    Article  Google Scholar 

  18. Feuer DJ, Broadley KE. Corticosteroids for the resolution of malignant bowel obstruction in advanced gynaecological and gastrointestinal cancer. The Cochrane Database of Systematic Reviews 1993;3.

  19. Pavlakis N, Schmidt RL, Stockler M. Bisphosphonates for breast cancer. The Cochrane Database of Systematic Reviews 2005;3.

  20. Djulbegovic B, Wheatley K, Ross J, et al. Bisphosphonates in multiple myeloma. The Cochrane Database of Systematic Reviews 2003;4.

  21. Bell R, Eccleston C, Kalso E. Ketamine as an adjuvant to opioids for cancer pain. The Cochrane Database of Systematic Reviews 2003;1.

  22. Menefee LA, Monti DA. Nonpharmacologic and complementary approaches to cancer pain management. J Am Osteopath Assoc 2005; 105(11 Suppl 5):S15-S20.

    PubMed  Google Scholar 

  23. Vickers AJ, Cassileth BR. Unconventional therapies for cancer and cancer-related symptoms. Lancet Oncol 2001;2(4):226–232.

    Article  CAS  PubMed  Google Scholar 

  24. Alimi D, Rubino C, Pichard-Leandri E, et al. Analgesic effect of auricular acupuncture for cancer pain: a randomized, blinded, controlled trial. J Clin Oncol 2003;21(22):4120–4126.

    Article  PubMed  Google Scholar 

  25. Cherny NI, Portenoy RK. The management of cancer pain. CA Cancer J Clin 1994;44(5):263–303.

    Article  CAS  PubMed  Google Scholar 

Download references

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Correspondence to Tyler Childs Cymet DO.

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The authors have stated that they do not have a significant financial interest or other relationship with any product manufacturer or provider of services discussed in this article. The authors do not discuss the use of off-label products, which includes unlabeled, unapproved, or investigative products or devices.

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Caimi, P., Cymet, T.C. As if the cancer wasn't enough! Understanding and treating the pain that comes with cancer . Compr Ther 32, 176–181 (2006). https://doi.org/10.1007/s12019-006-0009-2

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  • DOI: https://doi.org/10.1007/s12019-006-0009-2

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