Abstract
Aspirin increases anti-inflammatory aspirin-triggered lipoxin A4 levels in healthy subjects in a gender-specific manner in a randomized clinical study. Thus, formation of aspirin-triggered lipoxin A4 may provide a novel mechanism underlying aspirin's clinical benefits, and shed light on gender-dependent therapeutics of aspirin.
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The authors have stated that they do not have a significant financial interest or other relationship with any product manufacturer or provider of services discussed in this article. The authors do not discuss the use of off-label products, which includes unlabeled, unapproved, or investigative products or devices.
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Chiang, N., Serhan, C.N. New mechanism for an old drug Aspirin triggers anti-inflammatory lipid mediators with gender implications . Compr Ther 32, 150–157 (2006). https://doi.org/10.1007/s12019-006-0005-6
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DOI: https://doi.org/10.1007/s12019-006-0005-6