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Diagnosis and treatment of osteomyelitis

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Comprehensive Therapy

Abstract

The diagnosis and therapy of osteomyelitis remains difficult despite recent advances. Clinical decision making is also difficult because of considerable variations in the types of disease observed and the lack of large comparative trials studying the variety of approaches.

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References

  1. Bamberger DM, Diagnosis and treatment of osteomyelitis. Comp Ther. 1990;16:48–53.

    CAS  Google Scholar 

  2. Lew DP, Waldovogel FA. Osteomyelitis. N Engl J Med. 1997;336:999–1007.

    Article  PubMed  CAS  Google Scholar 

  3. Mader JT, Shirtliff M, Calhoun JH. Staging and staging application in osteomyelitis. Clin Infect Dis. 1997;25:1303–1309.

    PubMed  CAS  Google Scholar 

  4. Haas DW, McAndrew MP. Bacterial osteomyelitis in adults: evolving considerations in diagnosis and treatment. Am J Med 1996;101:550–559.

    Article  PubMed  CAS  Google Scholar 

  5. Vassilopoulos D, Chalasan P, Jurado RL, Workowski K, Agudelo CA. Musculoskeletal infections in patients with human immunodeficiency virus infection. Medicine. 1997; 76:284–294.

    Article  PubMed  CAS  Google Scholar 

  6. Lipskey BA, Osteomyelitis of the foot in diabetic patients. Clin Infect Dis. 1997;25:1318–1326.

    Google Scholar 

  7. Grayson ML, Gibbons GW, Balogh K, Levin E, Karchmer AW. Probing to bone in infected pedal ulcers. JAMA 1995; 273:712–720.

    Article  Google Scholar 

  8. Newman LG, Waller J, Palestro CJ, et al. Unsuspected osteomyelitis in diabetic foot ulcers: diagnosing and monitoring by leukocyte scanning with indium In111 oxyquinoline. JAMA. 1991;266:1246–1251.

    Article  PubMed  CAS  Google Scholar 

  9. Boutin RD, Brossmann J, Sartoris DJ, Reilly D, Resnick, D. Update on imaging of orthopedic infections. Orthop Clin North Am. 1998;29:41–66.

    Article  PubMed  CAS  Google Scholar 

  10. Craig JG, Amin MB, Wu K, et al. Osteomyelitis in the diabetic foot: MR imaging-pathologic correlation. Radiology. 1997;203:849–855.

    PubMed  CAS  Google Scholar 

  11. Morrison WB, Schweitzer ME, Wapner KL, et al. Osteomyelitis in the feet of diabetics: clinical accuracy, surgical utility, and cost-effectiveness of MR imaging. Radiology. 1995;196:557–564.

    PubMed  CAS  Google Scholar 

  12. Wheat LJ, Allen SD, Henry M, et al. Diabetic foot infections: bacteriologic analysis. Arch Intern Med. 1986;146: 1935–1940.

    Article  PubMed  CAS  Google Scholar 

  13. Darouiche RO, Landon GC, Klima M, Musher DM, Markowki J. Osteomyelitis associated with pressure sores. Arch Intern Med. 1994;154:756–758.

    Article  Google Scholar 

  14. Peltola H, Unkila-Kallio L, Kallio MJT, Finnish Study Group. Simplified treatment of acute staphylococcal osteomyelitis of childhood. Pediatrics. 1997;99:846–850.

    Article  PubMed  CAS  Google Scholar 

  15. Bell SM. Further observations on the value of oral penicillins in chronic staphylococcal osteomyelitis. Med J Austr. 1976;2:591–593.

    CAS  Google Scholar 

  16. Black J, Hunt TL, Godley PJ, Matthew E. Oral antimicrobial therapy for adults with osteomyelitis or septic arthritis. J Infect Dis. 1987;155:968–972.

    PubMed  CAS  Google Scholar 

  17. Kaplan SL, Mason EO Jr, Feigin RD. Clindamycin versus nafcillin or methicillin in the treatment of Staphylococcus aureus osteomyelitis in children. Southern Med J. 1982;75: 138–142.

    CAS  Google Scholar 

  18. Norden CW. Lessons learned from animal models of osteomyelitis. Rev Infect Dis. 1988;10:103–110.

    PubMed  CAS  Google Scholar 

  19. Norden CW, Bryant R, Palmer D, Montgomerie JZ, Wheat J. Chronic osteomyelitis caused by Staphylococcus aureus: controlled clinical trial of nafcillin therapy and nafcillinrifampin therapy. Southern Med J. 1986;79:947–951.

    Article  CAS  Google Scholar 

  20. Rissing JP. Antimicrobial therapy for chronic osteomyelitis in adults: role of the quinolones. Clin Infect Dis 1997;25: 1327–1333.

    PubMed  CAS  Google Scholar 

  21. Wininger DA, Fass RJ. Antibiotic-impregnated cement and beads for orthopedic infection. Antimicrob Agents Chemother. 1996;40:2675–2679.

    PubMed  CAS  Google Scholar 

  22. Zimmerli W, Widmer AF, Blatter M, Frei R, Ochsner PE Role of rifampin for treatment of orthopedic implant-related staphylococcal infections: a randomized controlled trial. Foreign-Body Infection (FBI) Study Group. JAMA. 1998;279: 1537–1541.

    Article  PubMed  CAS  Google Scholar 

  23. Ure KJ, Amstutz HC, Nasser S, Schmalzried TP. Directexchange arthroplasty for the treatment of infection after total hip replacement: an average ten-year follow-up. J Bone Joint Surg (Am). 1998;80:961–968.

    CAS  Google Scholar 

  24. Syrogiannopoulos GA, Nelson JD. Duration of antimicrobial therapy for acute suppurative osteoarticular infections. Lancet. 1988;1:37–40.

    Article  PubMed  CAS  Google Scholar 

  25. Bamberger DM, Daus GP, Gerding DN. Osteomyelitis in the feet of diabetic patients: long-term results, prognostic factors, and the role of antimicrobial and surgical therapy. Am J Med. 1987;83:653–660.

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Infectious Diseases Truman Medical Center, Kansas City, Mo

    David M. Bamberger MD (Professor of Medicine Chief)

  2. Fed 4 Unit, UMKC School of Medicine, 2411 Holmes St, 64108, Kansas City, MO

    David M. Bamberger MD (Professor of Medicine Chief)

Authors
  1. David M. Bamberger MD
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Bamberger, D.M. Diagnosis and treatment of osteomyelitis. Compr Ther 26, 89–95 (2000). https://doi.org/10.1007/s12019-000-0017-6

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  • DOI: https://doi.org/10.1007/s12019-000-0017-6

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