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Orthopedic Involvement in Antiphospholipid Syndrome

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Abstract

Antiphospholipid syndrome (APS) is a common autoimmune disease, manifested by vascular thrombosis and fetal loss in the presence of antiphospholipid antibodies. Orthopedic involvement is a relatively novel and underrecognized feature of APS. In this article we review the association of primary, secondary, and catastrophic APS with diverse orthopedic conditions, including osteonecrosis in adult and pediatric patients, bone marrow necrosis, nontraumatic fractures, and some other disorders.

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Authors and Affiliations

  1. Department of Internal Medicine E, Meir Hospital, Kfar Saba, 44281, Israel

    Alexander Gorshtein & Yair Levy

  2. Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel

    Alexander Gorshtein & Yair Levy

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  1. Alexander Gorshtein
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  2. Yair Levy
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Correspondence to Yair Levy.

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Gorshtein, A., Levy, Y. Orthopedic Involvement in Antiphospholipid Syndrome. Clinic Rev Allerg Immunol 32, 167–171 (2007). https://doi.org/10.1007/s12016-007-0006-y

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  • DOI: https://doi.org/10.1007/s12016-007-0006-y

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