Skip to main content

Advertisement

SpringerLink
Log in

A Case Report of Chemo-sensitive Intimal Pulmonary Artery Sarcoma

  • Translational Biomedical Research
  • Published:
Cell Biochemistry and Biophysics Aims and scope Submit manuscript

Abstract

The incidence rate of pulmonary artery sarcoma is very low, but its prognosis is extremely poor. In this case report, after various initial diagnoses at the early stage, pulmonary artery sarcoma was confirmed by surgery. 1 year later, the tumor recurred. After chemotherapy, the patient showed improvement of the subjective complaint of tightness in the chest, and radiological lesion decreased in size. The survival time was extended by 2.5 years. This is the first case report of pulmonary artery sarcoma with such chemo-sensitivity.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Mattoo, A., Fedullo, P. F., Kapelanski, D., & Ilowite, J. S. (2002). Pulmonary artery sarcoma: A case report of surgical cure and 5-year follow-up. Chest, 122, 745–747.

    Article  PubMed  Google Scholar 

  2. Tucci, M., Quatraro, C., Calvani, N., Serio, G., Marzullo, A., Dammacco, F., et al. (2005). Primary intimal sarcoma of the thoracic aorta. Journal of Experimental & Clinical Cancer Research, 24, 139–142.

    CAS  Google Scholar 

  3. Thalheimer, A., Fein, M., Geissinger, E., & Franke, S. (2004). Intimal angiosarcoma of the aorta: Report of a case and review of the literature. Journal of Vascular Surgery, 40, 548–553.

    Article  PubMed  Google Scholar 

  4. Osei-Agyemang, T., Geks, J., Wagner, H. J., Feek, U., & Gerdes, B. (2004). High-grade intimal sarcoma in an aneurysm of the infrarenal aorta. Chirurg, 75, 823–827.

    Article  CAS  PubMed  Google Scholar 

  5. Choi, E. Y., Yoon, Y. W., Kwon, H. M., Kim, D., Park, B. E., Hong, Y. S., et al. (2004). A case of pulmonary artery intimal sarcoma diagnosed with multislice CT scan with 3D reconstruction. Yonsei Medical Journal, 45, 547–551.

    PubMed  Google Scholar 

  6. Ozbek, C., Emrecan, B., Calli, A. O., & Gurbuz, A. (2007). Intimal sarcoma of the pulmonary artery with retrograde extension into the pulmonic valve and right ventricle. Texas Heart Institute Journal, 34, 119–121.

    PubMed Central  PubMed  Google Scholar 

  7. Araki, Y., Tajima, K., Yoshikawa, M., Abe, T., & Suenaga, Y. (1997). A case of primary pulmonary intimal sarcoma of the pulmonary artery. Nihon Kyobu Geka Gakkai Zasshi., 45, 1039–1043.

    CAS  PubMed  Google Scholar 

  8. Perez del Rio, M. J., Molina, S. R., Fresno Forcelledo, M. F., Veiga, G. M., Madrigal, R. B., Gonzalez, G. M., et al. (1998). An intimal sarcoma of the pulmonary artery. An immunohistochemical study. Revista Española de Cardiología, 51, 850–852.

    Article  CAS  PubMed  Google Scholar 

  9. Bode-Lesniewska, B., Zhao, J., Speel, E. J., Biraima, A. M., Turina, M., Komminoth, P., et al. (2001). Gains of 12q13–14 and overexpression of mdm2 are frequent findings in intimal sarcomas of the pulmonary artery. Virchows Archiv, 438, 57–65.

    Article  CAS  PubMed  Google Scholar 

  10. Zhang, H., Macdonald, W. D., Erickson-Johnson, M., Wang, X., Jenkins, R. B., & Oliveira, A. M. (2007). Cytogenetic and molecular cytogenetic findings of intimal sarcoma. Cancer Genetics and Cytogenetics, 179, 146–149.

    Article  CAS  PubMed  Google Scholar 

  11. Bretscher, P. A., Menon, J. N., & Ogunremi, O. (1996). Towards a strategy of universally efficacious vaccination against pathogens uniquely susceptible to cell-mediated attack. Journal of Biotechnology, 44, 1–4.

    Article  CAS  PubMed  Google Scholar 

  12. Sanchez-Munoz, A., Hitt, R., Artiles, V., Lopez, A., Hernandez, R., Cortes-Funes, H., et al. (2003). Primary aortic sarcoma with widespread vascular embolic metastases. European Journal of Internal Medicine, 14, 258–261.

    Article  PubMed  Google Scholar 

  13. Burke, A. P., & Virmani, R. (1993). Sarcomas of the great vessels, a clinicopathologic study. Cancer, 71, 1761–1773.

    Article  CAS  PubMed  Google Scholar 

  14. Hirose, T., Ishikawa, N., Hamada, K., Inagaki, T., Kusumoto, S., Shirai, T., et al. (2009). A case of intimal sarcoma of the pulmonary artery treated with chemoradiotherapy. Internal Medicine, 48, 245–249.

    Article  PubMed  Google Scholar 

  15. Uchida, A., Tabata, M., Kiura, K., Tanimoto, Y., Kanehiro, A., Aoe, M., et al. (2005). Successful treatment of pulmonary artery sarcoma by a two-drug combination chemotherapy consisting of ifosfamide and epirubicin. Japanese Journal of Clinical Oncology, 35, 417–419.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Tongji University Medical School Cancer Institute, Tongji University, No. 507 Zhengmin Road, Shanghai, 200433, People’s Republic of China

    Xiaoxia Chen, Shengxiang Ren, Aiwu Li & Caicun Zhou

Authors
  1. Xiaoxia Chen
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Shengxiang Ren
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Aiwu Li
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Caicun Zhou
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Caicun Zhou.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Chen, X., Ren, S., Li, A. et al. A Case Report of Chemo-sensitive Intimal Pulmonary Artery Sarcoma. Cell Biochem Biophys 68, 153–157 (2014). https://doi.org/10.1007/s12013-013-9681-x

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12013-013-9681-x

Keywords

Search

Navigation