Effects of Prenatal and Postnatal Exposure to GSM-Like Radiofrequency on Blood Chemistry and Oxidative Stress in Infant Rabbits, an Experimental Study
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We aimed to investigate the potential hazardous effects of prenatal and/or postnatal exposure to 1800 MHz GSM-like radiofrequency radiation (RFR) on the blood chemistry and lipid peroxidation levels of infant rabbits. A total of 72 New Zealand female and male white rabbits aged 1-month were used. Thirty-six female and 36 male were divided into four groups which were composed of nine infants: (i) Group 1 were the sham exposure (control), (ii) Group 2 were exposed to RFR, 15 min daily for 7 days in the prenatal period (between 15th and 22nd days of the gestational period) (prenatal exposure group). (iii) Group 3 were exposed to RFR 15 min/day (14 days for male, whereas 7 days for female) after they reached 1-month of age (postnatal exposure group). (iv) Group 4 were exposed to RFR for 15 min daily during 7 days in the prenatal period (between 15th and 22nd days of the gestational period) and 15 min/day (14 days for male, whereas 7 days for female) after they reached 1-month of age (prenatal and postnatal exposure group). Results showed that serum lipid peroxidation level in both female and male rabbits changed due to the RFR exposure. However, different parameters of the blood biochemistry were affected by exposure in male and female infants. Consequently, the whole-body 1800 MHz GSM-like RFR exposure may lead to oxidative stress and changes on some blood chemistry parameters. Studies on RFR exposure during prenatal and postnatal periods will help to establish international standards for the protection of pregnants and newborns from environmental RFR.
KeywordsRadiofrequency Mobile phone Children Lipid peroxidation Blood chemistry Rabbit
- 1.International Association for Maternal and Neonatal Health (IAMANEH). (2012). Retrieved October 2012 from http://www.gfmer.ch/000_IAMANEH.html.
- 2.World Health Organization (WHO). (2006). Research agenda for radio frequency fields. Retrieved October 2012 from http://www.who.int/peh-emf/research/rf_research_agenda_2006.pdf.
- 3.World Health Organization (WHO). (2011). International agency for research on cancer, press release 208: IARC classifies radiofrequency electromagnetic fields as possibly carcinogenic to human. Retrieved October 2012 from http://www.iarc.fr/en/media-centre/pr/2011/pdfs/pr208_E.pdf.
- 6.Young, M. E. (1996). Early child development: Investing in the Future. Washington, DC: The International Bank for Reconstruction and Development/The World Bank. ISBN 0-8213-3547-2.Google Scholar
- 9.Yoshioka, T., Kwada, K., Shimada, T., & Mori, M. (1979). Lipid peroxidation in maternal and cord blood and protective mechanisms against elevated oxygen toxicity in the blood. American Journal of Obstetrics and Gynecology, 135, 972–976.Google Scholar
- 22.Marino, C., Lagroye, I., Scarfì, M. R., & Sienkiewicz, Z. (2011). Are the young more sensitive than adults to the effects of radiofrequency fields? An examination of relevant data from cellular and animal studies. Progress in Biophysics and Molecular Biology, 107(3), 374–385.PubMedCrossRefGoogle Scholar
- 29.Kismali, G., Ozgur, E., Sayiner, S., Alpaslan, B., Guler, G., Seyhan, N., et al. (2009). The evaluation of epigallocatechin gallate and N-acetylcysteine on serum testosterone levels in male guinea pigs expose to cell phone microwave. Journal of Animal and Veterinary Advances, 8(6), 1149–1151.Google Scholar
- 40.Elliott, P., Toledano, M. B., Bennett, J., Beale, L., de Hoogh, K., Best, N., et al. (2010). Mobile phone base stations and early childhood cancers: Case–control study. British Medical Journal, 22, 340–347.Google Scholar