Skip to main content

Advertisement

Log in

Prevention of Hemodynamic Instability in Extra-Cranial Carotid Angioplasty and Stenting Using Temporary Transvenous Cardiac Pacemaker

  • Translational Biomedical Research
  • Published:
Cell Biochemistry and Biophysics Aims and scope Submit manuscript

Abstract

Hemodynamic instability is a common condition during extra-cranial carotid angioplasty and stenting (CAS). We evaluated the safety and efficacy of prophylactic placement of temporary cardiac pacemaker during extra-cranial CAS for the prevention of hemodynamic instability. For this, forty-seven carotid artery stents were deployed in 41 high-risk patients. Temporary transvenous cardiac pacemakers were inserted before CAS procedure. The pacers were set to capture a heart rate <60 bpm. Clinical symptoms, blood pressure, heart rate, and pacing activation were monitored and data were collected. We found that pacing occurred in 25 carotid lesions during balloon predilatation; pacemakers were activated transiently in 25 patients. The longest pacing continued for 1 day. Among cases with pacemaker activation, 1 patient developed post-procedural symptomatic hypotension that lasted for 4 days. No related complications were observed. It was, therefore, concluded that pacing was technically effective in producing electrical ventricular responses and was hemodynamically effective in 25 carotid lesions which underwent balloon predilatation. The prophylactic use of a temporary transvenous cardiac pacemaker during CAS was rapid and effective in controlling peri-operative hemodynamic instability and preventing stroke and other complications. The prophylactic use of temporary pacemaker is particularly recommended for patients at high risk for developing hemodynamic instability.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Gurm, H. S., Yadav, J. S., & Fayad, P. (2008). Long-term results of carotid stenting versus endarterectomy in high-risk patients. The New England Journal of Medicine, 358, 1572–1579.

    Article  PubMed  CAS  Google Scholar 

  2. Hanel, R. A., Xavier, A. R., & Kirmani, J. F. (2003). Management of carotid artery stenosis: Comparing endartercectomy and stenting. Current Cardiology Reports, 5, 153–159.

    Article  PubMed  Google Scholar 

  3. Brott, T. G., Hobson, R. W., 2nd., Howard, G., et al. (2010). Stenting versus endarterectomy for treatment of carotid-artery stenosis. The New England Journal of Medicine, 363, 11–23.

    Article  PubMed  CAS  Google Scholar 

  4. Bush, R. L., Lin, P. H., Bianco, C. C., et al. (2004). Reevaluation of temporary transvenous cardiac pacemaker usage during carotid angioplasty and stenting: a safe and valuable adjunct. Vascular and Endovascular Surgery, 38, 229–235.

    Article  PubMed  Google Scholar 

  5. Dangas, G., Laird, J. R., Satler, L. F., et al. (2000). Postprocedural hypotension after carotid artery stent placement: Predictors and short-and long-term clinical outcomes. Radiology, 215, 677–683.

    PubMed  CAS  Google Scholar 

  6. Mlekusch, W., Schillinger, M., Sabeti, S., et al. (2003). Hypotension and bradycardia after elective carotid stenting: Frequency and risk factors. Journal of Endovascular Therapy, 10, 851–859.

    Article  PubMed  Google Scholar 

  7. North American Symptomatic Carotid Endarterectomy Trail Collaborators. (1991). Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade stenosis. The New England Journal of Medicine, 325, 445–453.

    Article  Google Scholar 

  8. McKevitt, F. M., Macdonald, S., Venables, G. S., Cleveland, T. J., & Gaines, P. A. (2004). Complications following carotid angioplasty and carotid stenting in patients with symptomatic carotid artery disease. Cerebrovascular Disease, 17, 28–34.

    Article  CAS  Google Scholar 

  9. Qureshi, A. I., Luft, A. R., Sharma, M., et al. (1999). Frequency and determinants of postprocedural hemodynamic instability after carotid angioplasty and stenting. Stroke, 30, 2086–2093.

    Article  PubMed  CAS  Google Scholar 

  10. Qureshi, A. I., Luft, A. R., Lopes, D. K., et al. (1999). Postoperative hypotension after carotid angioplasty and stenting: Report of three cases. Neurosurgery, 44, 1320–1323.

    PubMed  Google Scholar 

  11. Mendelsohn, F. O., Weissman, N. J., Lederman, R. J., et al. (1998). Acute hemodynamic changes during carotid artery stenting. The American Journal of Cardiology, 82, 1077–1081.

    Article  PubMed  CAS  Google Scholar 

  12. Harrop, J. S., Sharan, A. D., Benitez, R. P., Armonda, R., Thomas, J., & Rosenwasser, R. H. (2001). Prevention of carotid angioplasty-induced bradycardia and hypotension with temporary venous pacemakers. Neurosurgery, 49, 814–820.

    PubMed  CAS  Google Scholar 

  13. Gupta, R., Abou-Chebl, A., Bajzer, C. T., Schumacher, H. C., & Yadav, J. S. (2006). Rate, Predictors, and consequences of hemodynamic depression after carotid artery stenting. Journal of the American College of Cardiology, 47, 1538–1543.

    Article  PubMed  Google Scholar 

  14. Gianaros, P. J., Jennings, J. R., Olafsson, G. B., et al. (2002). Greater intima media thickness in the carotid bulb is associated with reduced baroreflex sensitivity. American Journal of Hypertension, 15, 486–491.

    Article  PubMed  Google Scholar 

  15. Chao, A. C., Chern, C. M., Kuo, T. B., et al. (2003). Noninvasive assessment of spontaneous baroreflex sensitivity and heart rate variability in patients with carotid stenosis. Cerebrovascular Disease, 16, 151–157.

    Article  CAS  Google Scholar 

  16. Nonaka, T., Oka, S., Miyata, K., et al. (2005). Prediction of prolonged postprocedural hypotension after carotid artery stenting. Neurosurgery, 57, 472–477.

    Article  PubMed  Google Scholar 

  17. Lin, P. H., Zhou, W., Kougias, P., EI Sayed, H. F., Barshes, N. R., & Huynh, T. T. (2007). Factors associated with hypotension and bradycardia after carotid angioplasty and stenting. Journal of Vascular Surgery, 46, 846–853.

    Article  PubMed  Google Scholar 

  18. Taha, M. M., Toma, N., Sakaida, H., et al. (2008). Periprocedural hemodynamic instability with carotid angioplasty and stenting. Surgical Neurology, 70, 279–285.

    Article  PubMed  Google Scholar 

  19. Bussière, M., Lownie, S. P., Lee, D., Gulka, I., Leung, A., & Pelz, D. M. (2009). Hemodynamic instability during carotid artery stenting: the relative contribution of stent deployment versus balloon dilation. Journal of Neurosurgery, 110, 905–912.

    Article  PubMed  Google Scholar 

  20. Kojuri, J., Ostovan, M. A., Zamiri, N., Farshchizarabi, S., & Varavipoor, B. (2011). Hemodynamic instability following carotid artery stenting. Neurosurgery Focus, 30, E12.

    Article  Google Scholar 

  21. Caplan, L. R., & Hennerici, M. (1998). Impaired clearance of emboli (washout) is an important link between hypoperfusion, embolism, and ischemic stroke. Archives of Neurology, 55, 1475–1482.

    Article  PubMed  CAS  Google Scholar 

  22. Cayne, N. S., Rockman, C. B., & Maldonado, T. S. (2008). Hemodynamic changes associated with carotid artery interventions. Perspectives in Vascular Surgery and Endovascular Therapy, 20, 293–296.

    Article  PubMed  Google Scholar 

  23. Park, B. D., Divinagracia, T., Madej, O., et al. (2009). Predictors of clinically significant postprocedural hypotension after carotid endarterectomy and carotid angioplasty with stenting. Journal of Vascular Surgery, 50, 526–533.

    Article  PubMed  Google Scholar 

  24. Cayne, N. S., Faries, P. L., Trocciola, S. M., et al. (2005). Carotid angioplasty and stent-induced bradycardia and hypotension: impact of prophylactic atropine administration and prior carotid endarterectomy. Journal of Vascular Surgery, 41, 956–961.

    Article  PubMed  Google Scholar 

  25. Lim, H. H., Ho, K. M., Choi, W. Y., Teoh, G. S., & Chiu, K. Y. (2000). The use of intravenous atropine after a saline infusion in the prevention of spinal anesthesia-induced hypotension in elderly patients. Anesthesia Analgesia, 91, 1203–1206.

    PubMed  CAS  Google Scholar 

  26. Im, S. H., Han, M. H., Kim, S. H., & Kwon, B. J. (2008). Transcutaneous temporary cardiac pacing in carotid stenting: noninvasive prevention of angioplasty-induced bradycardia and hypotension. Journal of Endovascular Therapy, 15, 110–116.

    Article  PubMed  Google Scholar 

  27. Wang, J. L., Ling, F., Li, S. M., et al. (2006). Bradycardia during carotid artery stenting in proximal segmental stenosis and management strategy. Journal of Interventional Radiology, 15, 115–117.

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to Guo-en Yao or Hua-dong Zhou.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Liu, J., Yao, Ge., Zhou, Hd. et al. Prevention of Hemodynamic Instability in Extra-Cranial Carotid Angioplasty and Stenting Using Temporary Transvenous Cardiac Pacemaker. Cell Biochem Biophys 65, 275–279 (2013). https://doi.org/10.1007/s12013-012-9429-z

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12013-012-9429-z

Keywords

Navigation