Skip to main content

The Prevalence of Type 2 Diabetes and Hypertension in Uygur and Kazak Populations

Cardiovascular Toxicology volume 8, pages 155–159 (2008)Cite this article

Abstract

This study was designed to evaluate the epidemiology of type 2 diabetes and hypertension in Uygur and Kazak ethnic populations. A three-step stratified sampling method was used. Questionnaires, blood pressure, anthropometric measurement, and fasting blood glucose were monitored. In total, 1,571 Uygur and 2,913 Kazak subjects were randomly enrolled. The prevalence of type 2 diabetes and glucose intolerance was 5.55- and 1.90-fold higher, respectively, in Uygur than in the Kazak population (8.16 vs. 1.47%, P < 0.001 and 3.29 vs. 1.73%, P < 0.001). However, the prevalence of hypertension and obesity was significantly higher in the Kazak than in the Uygur population (hypertension: 43.52 vs. 31.98%, P < 0.001; obesity: 25.0 vs. 14.5%, P < 0.001, respectively). Our data suggest a significantly different prevalence in hypertension, hyperlipidemia, and type 2 diabetes between the two ethnic groups. The prevalence of type 2 diabetes was much lower, while the prevalence of hypertension was much higher associated with a higher incidence of obesity in the Kazak population. Individuals with a greater BMI and blood pressure were more prone to development of type 2 diabetes. Our data revealed that waist circumference of Kazak ethnics was greater than that of Uygur, even at the same BMI level. Serum fasting glucose was associated with different factors in Uygur and Kazak.

This is a preview of subscription content, access via your institution.

Access options

Buy single article

Instant access to the full article PDF.

43,34 €

Price includes VAT (Finland)
Tax calculation will be finalised during checkout.

Fig. 1

References

  1. World Health Organization. (1999). Definition, diagnosis and classification of diabetes mellitus and its complications: Report of a WHO consultation. Part 1: Diagnosis and classification of diabetes mellitus. Geneva, WHO (WHO/NCD/NCS/99.2).

  2. Yan, W., Yang, X., Zheng, Y., Ge, D., Zhang, Y., Shan, Z., et al. (2005). The metabolic syndrome in Uygur and Kazak populations. Diabetes Care, 28, 2554–2555. doi:10.2337/diacare.28.10.2554.

    PubMed  Article  Google Scholar 

  3. Gu, D., Reynolds, K., Wu, X., Chen, J., Duan, X., Reynolds, R. F., et al., Inter-ASIA Collaborative Group. (2005). Prevalence of the metabolic syndrome and overweight among adults in China. Lancet, 365, 1398–1405. doi:10.1016/S0140-6736(05)66375-1.

    PubMed  Article  Google Scholar 

  4. International Diabetes Federation. The IDF consensus worldwide definition of the metabolic syndrome. http://www.metabolicsyndromeinstitute.com/medicalinformation/literaturereview/2005/document.2005-05-19.5770709184.

  5. James, W. P. (2008). The epidemiology of obesity: The size of the problem. Journal of Internal Medicine, 263, 336–352. doi:10.1111/j.1365-2796.2008.01922.x.

    PubMed  Article  CAS  Google Scholar 

  6. Gu, D., Reynolds, K., Duan, X., Xin, X., Chen, J., Wu, X., et al., Inter ASIA Collaborative Group. (2003). Prevalence of diabetes and impaired fasting glucose in the Chinese adult population: International Collaborative Study of Cardiovascular Disease in Asia (InterASIA). Diabetologia, 46, 1190–1198. doi:10.1007/s00125-003-1167-8.

    PubMed  Article  CAS  Google Scholar 

  7. Wu, H. Y., Chen, L. L., Zheng, J., Liao, Y. F., & Zhou, M. (2007). Simple anthropometric indices in relation to cardiovascular risk factors in Chinese type 2 diabetic patients. The Chinese Journal of Physiology, 3, 135–142.

    Google Scholar 

  8. Li, L. L., Zhang, Y. M., Du, J. Y., Mao, X. M., Wu, X. H., Ran, X. J., et al. (2005). Analysis of metabolic features and food composition related with pathogenesis of type 2 diabetes mellitus in population of Uigurs and Kazaks in Xinjiang. Chinese Journal of Endocrinology and Metabolism, 21, 141–142.

    Google Scholar 

  9. Huxley, R., & James, W. P. (2008). Ethnic comparisons of the cross-sectional relationships between measures of body size with diabetes and hypertension. Obesity Reviews, 1, 53–61. doi:10.1111/j.1467-789X.2007.00439.x.

    Article  Google Scholar 

  10. Feng, Y., Zang, T., Xu, X., & Xu, X. (2008). Familial aggregation of metabolic syndrome and its components in a large Chinese population. Obesity, 1, 125–129.

    Article  Google Scholar 

  11. Tseng, C. H. (2007). Body mass index and blood pressure in adult type 2 diabetic patients in Taiwan. Circulation Journal, 11, 1749–1754.

    Article  Google Scholar 

Download references

Acknowledgments

The study was supported by the Technology Government Agency of Xinjiang Uygur Autonomous Region. This study was supported in part by the Inter-centennial Outstanding Talent Scholarship from the Ministry of Education, People’s Republic of China (2005–2008, NCET-04-0992), the National Natural Science Foundation of China (30660211, 30660288) and Xinjiang Uygur autonomic Tackle Key Problems Plans (2006–2008, 200633129). The work also received support from Diabetes Vip lab of First affiliated Hospital of Xinjiang Medical University. The authors wish to thank all participants of this study.

Author information

Affiliations

  1. Division of Pharmacology, School of Pharmacy, Xinjiang Medical University, 8 Xinyi Rd, Urumqi, 830054, Xinjiang Uygur Autonomous Region, China

    Yicun Tao, Xinmin Mao, Xinjian Ran, Xiaoyan Liu, Ye Wang, Xin Luo, Mengying Hu, Wenning Gen, Minfang Zhang, Tao Wang, Hamulati Wufuer & Linlin Li

  2. Department of Endocrinology, First Affiliate Hospital of Xinjiang Medical University, Urumqi, Xinjiang Uygur Autonomous Region, China

    Zijing Xie

  3. Center for Cardiovascular Research and Alternative Medicine, University of Wyoming College of Health Sciences, Laramie, WY, 82071, USA

    Jun Ren

Authors
  1. Yicun Tao
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Xinmin Mao
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Zijing Xie
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Xinjian Ran
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Xiaoyan Liu
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Ye Wang
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Xin Luo
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Mengying Hu
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Wenning Gen
    View author publications

    You can also search for this author in PubMed Google Scholar

  10. Minfang Zhang
    View author publications

    You can also search for this author in PubMed Google Scholar

  11. Tao Wang
    View author publications

    You can also search for this author in PubMed Google Scholar

  12. Jun Ren
    View author publications

    You can also search for this author in PubMed Google Scholar

  13. Hamulati Wufuer
    View author publications

    You can also search for this author in PubMed Google Scholar

  14. Linlin Li
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Jun Ren.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Tao, Y., Mao, X., Xie, Z. et al. The Prevalence of Type 2 Diabetes and Hypertension in Uygur and Kazak Populations. Cardiovasc Toxicol 8, 155–159 (2008). https://doi.org/10.1007/s12012-008-9024-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12012-008-9024-0

Keywords

  • Type 2 diabetes
  • Hypertension
  • Uygur
  • Kazak
  • Ethnicity