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Multi-element Characteristics of Chinese Medical Baishao (Paeoniae Radix Alba) and Their Decoctions

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Abstract

Adopting ICP-AES and ICP-MS to determine the content of 53 elements (6 macro-elements, 47 trace elements), which used HNO3 (5 mL) and H2O2 (2 mL) to digest Baishao (Paeoniae Radix Alba) by microwave. These herbs obtained from six producing areas in China, namely Xuanwu (Henan province), Shihezi (Xinjiang province), Zhongjiang (Sichuan province), Panan (Zhejiang province), Bozhou (Anhui province), and Heze (Shandong province). A certified reference material of Astragalus (GBW 10028, GSB-19) was used to assess the accuracy of the method. Except the slight change of Na and S in Xuanwu, the content of other producing areas followed the order of Ca > K > P > Mg > S > Na. The herbs of Shihezi (22,658 mg/kg) got the highest concentration of total elements, while the herbs of Panan (1.006 mg/kg) got the highest concentration of rare earth elements. The multi-element fingerprint map of Baishao was established, which was obviously different from other herbs. Meanwhile, the same method was adopted to determine the content of 50 elements in Baishao decoctions from three main producing areas. Compared with the herbs, each element was significantly reduced, and K was the highest concentration. The transfer rates of elements in Baishao decoctions followed the order (mean): As (55.79%) > Ni (55.19%) > Na (51.48%) > Mo (44.13%) > Ce (43.82%) > V (40.52%). The decoctions of Panan (0.122 mg/kg) got the highest content of rare earth elements. In all Baishao herbs and their corresponding decoctions, the levels of Cu, Cd, As, Pb, and Hg did not exceed the limits of the Green Trade Standards of Importing & Exporting Medicinal Plants & Preparations (WM2-2001) and Chinese Pharmacopoeia (2015).

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Funding

This work was finically supported by National Key R&D Program of China (2018YFC1707004) and the Key project of Anhui University of Traditional Chinese Medicine (2018zrzd07).

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Authors and Affiliations

  1. CAS Key Laboratory of Crust-Mantle Materials and Environment, School of Earth and Space Sciences, University of Science and Technology of China, Hefei, 230026, Anhui, China

    Xuan Xue, Guijian Liu & Yong Wei

  2. School of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012, China

    Xuan Xue, Feng Li, Delin Wu & Wei Zhang

  3. Anhui Province Key Laboratory of Traditional Chinese Medicine Decoction Pieces of New Manufacturing Technology, Hefei, 230012, China

    Xuan Xue

  4. State Key Laboratory of Coal Combustion, School of Energy and Power Engineering, Huazhong University of Science and Technology, Wuhan, 430074, China

    Biao Fu

  5. Anhui Xiehecheng Co., Ltd, Bozhou, 236800, China

    Wei Zhang

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  1. Xuan Xue
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Correspondence to Guijian Liu.

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Xue, X., Liu, G., Wei, Y. et al. Multi-element Characteristics of Chinese Medical Baishao (Paeoniae Radix Alba) and Their Decoctions. Biol Trace Elem Res 199, 2375–2386 (2021). https://doi.org/10.1007/s12011-020-02343-0

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