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Enhancement in Iron Absorption on Intake of Chemometrically Optimized Ratio of Probiotic Strain Lactobacillus plantarum 299v with Iron Supplement Pearl Millet

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Abstract

This research article aims to establish the intake ratio of probiotic Lactobacillus plantarum 299v with iron supplement pearl millet by central composite design of response surface methodology so as to enhance iron absorption. In anemic rat models, the food intake pattern, body weight, hemoglobin content, and hematocrit values were found to be significantly increased on treatment with pearl millet:probiotic; however, incorporation of probiotics at lower dose (0.5 g) was significantly (p < 0.05) effective in enhancing iron absorption, and further increment in probiotic doses (1.0 g) did not produce significant increase in hemoglobin and hematocrit values as evidenced by the experimental findings.

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Acknowledgements

We thank the Nirmala College of Pharmacy, Mangalagiri, Guntur, Andhra Pradesh, India, for providing research facilities.

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Authors and Affiliations

  1. Nirmala College of Pharmacy, Mangalagiri, Guntur, Andhra Pradesh, India

    Shanta Kumari Adiki, Chandra Kiran Perla & Vinaykumar Theendra

  2. Research Officer, National Tea Research Foundation, Kolkata, India

    Gargi Saha

  3. Indira College of Pharmacy, Nanded, Maharashtra, India

    Prakash Katakam

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  1. Shanta Kumari Adiki
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  2. Chandra Kiran Perla
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  3. Gargi Saha
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  4. Prakash Katakam
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  5. Vinaykumar Theendra
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Correspondence to Shanta Kumari Adiki.

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Adiki, S.K., Perla, C.K., Saha, G. et al. Enhancement in Iron Absorption on Intake of Chemometrically Optimized Ratio of Probiotic Strain Lactobacillus plantarum 299v with Iron Supplement Pearl Millet. Biol Trace Elem Res 190, 150–156 (2019). https://doi.org/10.1007/s12011-018-1541-5

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  • DOI: https://doi.org/10.1007/s12011-018-1541-5

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