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Effects of Selenium and Cadmium on Ion Profiles in the Brains of Chickens

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Abstract

Antagonistic effects of selenium (Se) in cadmium (Cd)-induced toxicity have been frequently reported in previous studies. However, little was known about the interactions of Se and Cd on ion profiles in the brains of poultry. The aim of this study was to investigate the interaction between Se and Cd in the ion profile of the chicken brain. In the present study, a total of 128 laying hens were fed a Se-, Cd-, or Se + Cd-supplemented diet for 90 days. Levels of 28 ions were detected in chicken brains using ICP-MS. We found that Cd exposure significantly increased the content of Cd in the brain; furthermore, the content of lithium (Li), stannum (Sn), and stibium (Sb) increased, but the content of kalium (K) decreased. The content of Se in the brain was not altered by Se supplementation; however, Se reduced the concentrations of Sn and Sb, which in contrast were increased by Cd exposure. Complex interactions between ions were analyzed by principal component analysis, and both positive and negative correlations between different ions were found after prolonged exposure to Se and Cd. These findings suggest that Se and Cd supplementation influences the ion profiles in the chicken brain, and moreover, Se may have an antagonistic effect under longer exposure to Cd.

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Acknowledgments

This work was supported by the Heilongjiang Postdoctoral Fund (Grant No. LBH-Z14223) and the Natural Science Foundation of the Heilongjiang Province of China (Grant No. C200932).

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Authors and Affiliations

  1. College of Animal Science and Technology, Northeast Agricultural University, Harbin, 150030, China

    Runxiang Zhang, Lisha Wang, Jianing Zhao, Chao Wang & Jun Bao

  2. College of Life Science, Northeast Agricultural University, Harbin, 150030, China

    Jianhong Li

Authors
  1. Runxiang Zhang
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  2. Lisha Wang
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  3. Jianing Zhao
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  4. Chao Wang
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  5. Jun Bao
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  6. Jianhong Li
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Corresponding authors

Correspondence to Jun Bao or Jianhong Li.

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All procedures performed in the present study were approved by the Institutional Animal Care and Use Committee of Northeast Agriculture University.

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The authors declare that they have no conflict of interest.

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Zhang, R., Wang, L., Zhao, J. et al. Effects of Selenium and Cadmium on Ion Profiles in the Brains of Chickens. Biol Trace Elem Res 174, 218–225 (2016). https://doi.org/10.1007/s12011-016-0693-4

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  • DOI: https://doi.org/10.1007/s12011-016-0693-4

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