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The Effect of Age on 12 Chemical Element Contents in the Intact Prostate of Adult Men Investigated by Inductively Coupled Plasma Atomic Emission Spectrometry

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Abstract

The effect of age on 12 chemical element contents in intact prostate of 64 apparently healthy, 13–60-year-old men (mean age 36.5 years) was investigated by inductively coupled plasma atomic emission spectrometry. Mean values (M ± SΕΜ) for mass fraction (milligrams/kilogram, on dry weight basis) of Ba, Ca, Cu, Fe, K, Mg, Na, P, S, Sr, and Zn were: Ba 1.18 ± 0.12, Ca 2,178 ± 160, Cu 10.7 ± 0.9, Fe 122 ± 5, K 12,530 ± 360, Mg 1,100 ± 70, Na 10,470 ± 320, P 7,580 ± 300, S 8,720 ± 180, Sr 1.85 ± 0.28, and Zn 782 ± 97, respectively. The upper limit of mean content of V was ≤0.22 mg/kg. A tendency of age-related increase in Ca, Fe, Na, and Zn mass fraction as well an increase in Zn/Ba, Zn/Ca, Zn/Cu, Zn/Fe, Zn/K, Zn/Mg, Zn/Na, Zn/P, Zn/S, and Zn/Sr ratios in prostate was observed. A significant positive correlation was seen between the prostatic zinc and Ca, Cu, Fe, Mg, Na, and P contents.

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Acknowledgments

The authors are grateful to Prof. A.A. Zhavoronkov, Institute of Human Morphology, Russian Academy of Medical Sciences, Moscow for supplying prostate samples, and acknowledge the support of the Presidium of Russian Academy of Sciences, program for basic research: “Creation and improvement of methods of chemical analysis, and investigation of substances and material structure.”

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  1. Radionuclide Diagnostics Department, Medical Radiological Research Centre, Russian Academy of Medical Sciences, Koroleva Str.-4, Obninsk, 249020, Kaluga Region, Russia

    Vladimir Zaichick

  2. Institute of Microelectronics Technology and High Purity Materials, Chernogolovka, 142432, Russia

    Sergey Nosenko & Irina Moskvina

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  1. Vladimir Zaichick
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Correspondence to Vladimir Zaichick.

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Zaichick, V., Nosenko, S. & Moskvina, I. The Effect of Age on 12 Chemical Element Contents in the Intact Prostate of Adult Men Investigated by Inductively Coupled Plasma Atomic Emission Spectrometry. Biol Trace Elem Res 147, 49–58 (2012). https://doi.org/10.1007/s12011-011-9294-4

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