Comparison of Hypoglycemic Activity of Fermented Mushroom of Inonotus obliquus Rich in Vanadium and Wild-Growing I. obliquus

Abstract

The effects of vanadium-enriched and wild Inonotus obliquus were tested on hyperglycemic mice. The vanadium content of the culture medium was 0.6%, reaching a concentration of 3.0 mg/g in the cultured mushroom while in the wild variety is 1/100 of that amount. The toxicity of vanadium at the 3.0 mg/g level is negligible, but its anti-diabetic effects are significantly different to those of the wild variety (p < 0.05). Due to its high bioavailability and low toxicity, vanadium-enriched I. obliquus could be used as a means of vanadium supplementation, with expectation of obtaining higher bioavailability and lower toxicity in animals.

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Acknowledgments

This research was supported by project from the Chongqing Education committee (KJ090311).

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Correspondence to Sha Liu.

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Zhang, Y., Zhao, Y., Cui, H. et al. Comparison of Hypoglycemic Activity of Fermented Mushroom of Inonotus obliquus Rich in Vanadium and Wild-Growing I. obliquus . Biol Trace Elem Res 144, 1351–1357 (2011). https://doi.org/10.1007/s12011-011-9043-8

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Keywords

  • Vanadium
  • Inonotus obliquus
  • AAS
  • Blood glucose