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Chromium and Manganese Levels in Biological Samples of Normal and Night Blindness Children of Age Groups (3–7) and (8–12) Years

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An Erratum to this article was published on 22 December 2010

Abstract

This study was designed to compare the levels of chromium (Cr) and manganese (Mn) in scalp hair, blood, and urine of night blindness in children age ranged (3–7) and (8–12) years of both genders, comparing them to sex- and age-matched controls. A microwave-assisted wet acid digestion procedure, was developed as a sample pretreatment, for the determination of Cr and Mn in biological samples of night blindness children. The proposed method was validated by using conventional wet digestion and certified reference samples of hair, blood and urine. The digests of all biological samples were analyzed for Cr and Mn by electrothermal atomic absorption spectrometry. The results indicated significantly higher levels of Cr, whilst low level of Mn in the biological samples (blood and scalp hair) of male and female night blindness children, compared with control subjects of both genders. These data present guidance to clinicians and other professional investigating deficiency of Mn and excessive level of Cr in biological samples (scalp hair and blood) of night blindness children.

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Acknowledgement

The authors would like to thank the Higher Education Commission, Islamabad, Pakistan, for sponsoring this project.

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Authors and Affiliations

  1. National Center of Excellence in Analytical Chemistry, University of Sindh, Jamshoro, Pakistan

    Hassan Imran Afridi, Tasneem Gul Kazi, Ghulam Abbas Kandhro, Abdul Qadir Shah, Jameel Ahmed Baig, Sham Kumar Wadhwa, Sumaira Khan, Nida Fatima Kolachi, Faheem Shah, Mohammad Khan Jamali & Mohammad Balal Arain

  2. Mechanical and Manufacturing Engineering, Dublin City University, Dublin, Ireland

    Hassan Imran Afridi

  3. Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan

    Naveed Kazi

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  1. Hassan Imran Afridi
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  2. Tasneem Gul Kazi
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Correspondence to Hassan Imran Afridi.

Additional information

An erratum to this article can be found at http://dx.doi.org/10.1007/s12011-010-8927-3

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Afridi, H.I., Kazi, T.G., Kazi, N. et al. Chromium and Manganese Levels in Biological Samples of Normal and Night Blindness Children of Age Groups (3–7) and (8–12) Years. Biol Trace Elem Res 143, 103–115 (2011). https://doi.org/10.1007/s12011-010-8851-6

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