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Serum Trace Element Levels in Tuberculous Pleurisy

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Abstract

In this study, copper, zinc, magnesium, manganese, selenium, and iron were measured by inductively coupled plasma atomic emission spectrophotometry in patients with tuberculous (TB) pleurisy (n = 24) and in the control group (n = 20). Selenium, magnesium, and zinc were found to be significantly lower in TB pleurisy cases than those in the control group (p < 0.01, p < 0.001, and p < 0.001, respectively). There was no significant difference in the value of manganese and iron between TB pleurisy and the control group (p > 0.05). Copper levels were significantly increased in the serum of the patients (p < 0.0001). These results may provide an additional disease correlate for assessing TB pleurisy risk.

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References

  1. Sakuraba M, Masuda K, Hebisawa A, Sagara Y, Komatsu H (2009) Pleural effusion adenosine deaminase (ADA) level and occult tuberculous pleurisy. Ann Thorac Cardiovasc Surg 15(5):294–296

    PubMed  Google Scholar 

  2. Gopi A, Madhavan SM, Sharma SK, Sahn SA (2007) Diagnosis and treatment of tuberculous pleural effusion in 2006. Chest 1:880–889

    Article  Google Scholar 

  3. Trajman A, Pai M, Dheda K, van Zyl SR, Zwerling AA et al (2008) Novel tests for diagnosing tuberculous pleural effusion: what works and what does not? Eur Respir J 31:1098–1106

    Article  PubMed  CAS  Google Scholar 

  4. Pai M, Flores LL, Hubbard A, Riley LW, Colford JM Jr (2004) Nucleic acid amplification tests in the diagnosis of tuberculous pleuritis: a systematic review and meta-analysis. BMC Infect Dis 4:6

    Article  PubMed  Google Scholar 

  5. Chen ML, Yu WC, Lam CW, Au KM, Kong FY et al (2004) Diagnostic value of pleural fluid adenosine deaminase activity in tuberculous pleurisy. Clin Chim Acta 341:101–107

    Article  PubMed  CAS  Google Scholar 

  6. Titarenko OT, D’iakova ME, Perova TL, D’iakova AI, Popov MIu (2002) Informative value of adenosine deaminaze and 2-deoxyadenosine deaminase in the diagnosis of tuberculous pleurisy. Klin Lab Diagn 5:11–14 (in Russian)

    PubMed  Google Scholar 

  7. Sharma SK, Suresh V, Mohan A, Kaur P, Saha P et al (2001) A prospective study of sensitivity and specificity of adenosine deaminase estimation in the diagnosis of tuberculosis pleural effusion. Indian J Chest Dis Allied Sci 43:149–155

    PubMed  CAS  Google Scholar 

  8. Bueso FJ, Hernando VH, Garcia-Buela JP, Juncal DL, Egana MMT et al (1988) Diagnostic value of simultaneous determination of pleural adenosine deaminase and pleural lysozyme/serum lysozyme ratio in pleural effusions. Chest 93:303–307

    Article  Google Scholar 

  9. Ocana I, Martinez-Vazquez JM, Segura RM, Fernandez-De-Sevilla T, Capdevila JA (1983) Adenosine deaminase in pleural fluids. Test for diagnosis of tuberculous pleural effusion. Chest 84:51–53

    Article  PubMed  CAS  Google Scholar 

  10. Chunchao H, Junhua Y, Yingzi W, Lingjun L (2006) Hypoglycemic activity of fermented mushroom of Coprinus comatus rich in vanadium. J Trace Elem Med Biol 20:191–196

    Article  Google Scholar 

  11. Han C (2009) Comparison of anti-hyperglycemic effect of inorganic constituents and organic in traditional Chinese medicine, Jinqi compound recipe. Biol Trace Elem Res 131(1):55–61

    Article  PubMed  CAS  Google Scholar 

  12. Parr RM, Taylor DM (1964) The concentrations of cobalt, copper, iron and zinc in some normal human tissues as determined by neutron-activation analysis. Biochem J 91:424

    PubMed  CAS  Google Scholar 

  13. Charles B, Clayman (1989) American medical association. Am Med Assoc/Encycl Med 396:605–752

    Google Scholar 

  14. Muralidhar LH (2004) Serum trace element levels and the complexity of inter element relations in patients with Parkinson’s disease. J Trace Elem Med Biol 18:163–171

    Article  Google Scholar 

  15. Christianson DW (1991) Structural biology of zinc. Adv Protein Chem 142:281–355

    Article  Google Scholar 

  16. Celik HA, Aydin HH, Ozsaran A, Kilincsoy N, Batur Y, Ersoz B (2002) Trace elements analysis of ascitic fluid in benign and malignant diseases. Clin Biochem 35(6):477–481

    Article  PubMed  Google Scholar 

  17. Vallee B, Coleman J, Auld D (1991) Zinc fingers, zinc clusters, and zinc twists in DNA-binding protein domains. Proc Natl Acad Sci U S A 88:999–1003

    Article  PubMed  CAS  Google Scholar 

  18. Vallee B, Falchuk K (1993) The biochemical basis of zinc physiology. Physiol Rev 73:79–118

    PubMed  CAS  Google Scholar 

  19. Han C, Li J, Hui Q (2008) Determination of trace elements in Jinqi, a traditional Chinese medicine. Biol Trace Elem Res 122(2):122–126

    Article  PubMed  CAS  Google Scholar 

  20. Blanchard R, Cousins R (1996) Differential display of intestinal mRNAs regulated by dietary zinc. Proc Natl Acad Sci U S A 93:6863–6868

    Article  PubMed  CAS  Google Scholar 

  21. Chesters J, Petrie L, Travis A (1990) A requirement for Zn2+ for the induction of thymidine kinase but not ornithine decarboxylase in 3 T3 cells stimulated from quiescence. Biochem J 272:525–527

    PubMed  CAS  Google Scholar 

  22. Pekarek RS, Wannemacher RW Jr, Beisel WR (1972) Effect of leukocytic endogenous mediator (LEM) on the tissue distribution of zinc and iron. Proc Soc Exp Biol Med 140:685–688

    PubMed  CAS  Google Scholar 

  23. Beyenbach KW (1990) Transport of magnesium across biological membranes. Magnes Trace Elem 9:233–254

    PubMed  CAS  Google Scholar 

  24. Williams RJP (1970) The biochemistry of sodium, potassium, magnesium and calcium. Q Rev Chem Soc 24:331–365

    Article  CAS  Google Scholar 

  25. Schrauzer GN, Rhead WJ, Evans GA (1973) Selenium and cancer. Chemical interpretation of a plasma cancer test. Bioinorgan Chem 2:329–340

    Article  CAS  Google Scholar 

  26. Shamberger RJ, Rukovena E, Longfield AK, Tytko SA, Deodher S, Willis CE (1973) Antioxidants and cancer. I. Selenium in the blood of normals and cancer patients. J Nat Cancer Inst 50:863–870

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Respiratory, Shandong Chest Hospital, Jinan, 250013, People’s Republic of China

    Guang-Qiang Wang & Mei-Ying Lin

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  1. Guang-Qiang Wang
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  2. Mei-Ying Lin
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Correspondence to Mei-Ying Lin.

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Wang, GQ., Lin, MY. Serum Trace Element Levels in Tuberculous Pleurisy. Biol Trace Elem Res 141, 86–90 (2011). https://doi.org/10.1007/s12011-010-8722-1

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  • DOI: https://doi.org/10.1007/s12011-010-8722-1

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