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Effect of Training Judo in the Competition Period on the Plasmatic Levels of Leptin and Pro-inflammatory Cytokines in High-Performance Male Athletes

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Abstract

The purpose this study was to evaluate the effect of training judo in the competition period on the plasmatic levels of bioactive molecules in high-performance male athletes. The subjects were divided into two groups, a trained group with 11 judokas and a nontrained group also with 11 subjects. Blood samples obtained 60 h after training to measure plasma tumor necrosis factor (TNF-α), interleukin-6 (IL-6), monocyte chemotactic protein 1 (MCP-1), and leptin levels. The trained group presented a significant reduction in the percentage of fat and fat mass and an increase in the lumbar and lower limbs traction forces and the maximum VO2 when compared to the nontrained group. There was no significant difference in the serum concentrations of TNF-α and IL-6 between the two groups. The trained group presented a lower concentration of leptin, both as absolute values as well as relative to the percentage of fat, and a higher concentration of MCP-1, in relation to the nontrained group. Our results suggest an adaptation in the capacity of synthesizing and secreting leptin in response to chronic stress in judo, what suggests a neuro-hormonal adjustment that guarantees the efficiency of metabolism. The changes of MCP-1 indicated a possible inflammatory state.

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Authors and Affiliations

  1. Post Graduate Program—Human Movement Sciences Institute of Physical Activity and Sport Sciences, Cruzeiro do Sul University São Paulo, 868 Galvão Bueno Street, São Paulo, 01506-000, SP, Brazil

    Donizete Cicero Xavier de Oliveira, Izildinha Rossano Procida & Cristina das Neves Borges-Silva

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  1. Donizete Cicero Xavier de Oliveira
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  2. Izildinha Rossano Procida
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  3. Cristina das Neves Borges-Silva
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Correspondence to Cristina das Neves Borges-Silva.

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de Oliveira, D.C.X., Rossano Procida, I. & das Neves Borges-Silva, C. Effect of Training Judo in the Competition Period on the Plasmatic Levels of Leptin and Pro-inflammatory Cytokines in High-Performance Male Athletes. Biol Trace Elem Res 135, 345–354 (2010). https://doi.org/10.1007/s12011-009-8499-2

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