Skip to main content
Log in

Prevalence of Age-Related Cataract in High-Selenium Areas of China

  • Published:
Biological Trace Element Research Aims and scope Submit manuscript

Abstract

The objective of this study was to determine the prevalence of age-related cataract in high-selenium areas of China. This is a cross-sectional study of 1,522 persons aged 50 years and more who were selected as a representative sample from the Enshi prefecture in Hubei province. All lenses were graded and classified for opacities by slit lamp after papillary dilation, using the Lens Opacification Classification System II. The age-related cataract patients were 418 cases (33.28%). The prevalence of age-related cataract was 37.2% in women and 26.0% in men. The prevalence of nuclear cataract was 23.7%; cortical cataract was 22.4% and posterior subcapsule cataract was 5.2%. The prevalence of cataract of the 50–59 group was 13.41%; 60–69 group was 42.15%; 70 and over group was 61.9%. The prevalence of age-related cataract in high-selenium areas has not significantly increased; to some extent, the high selenium intake will not become a risk factor for the increase of cataract incidence.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Brauer VF, Schweizer U, Köhrle J, Paschke R (2006) Selenium and goiter prevalence in borderline iodine sufficiency. Eur J Endocrinol 155:807–812

    Article  PubMed  CAS  Google Scholar 

  2. Karaküçük S, Ertugrul Mirza G, Faruk Ekinciler O, Saraymen R, Karaküçük I, Ustdal M (1995) Selenium concentrations in serum, lens and aqueous humour of patients with senile cataract. Acta Ophthalmol Scand 73:329–332

    Article  PubMed  Google Scholar 

  3. Jacques PF, Hartz SC, Chylack LT Jr, McGandy RB, Sadowski JA (1988) Nutritional status in persons with and without senile cataract: blood vitamin and mineral levels. Am J Clin Nutr 48:152–158

    PubMed  CAS  Google Scholar 

  4. Shearer TR, Ma H, Fukiage C, Azuma M (1997) Selenite nuclear cataract: review of the model. Mol Vis 23(3):8

    Google Scholar 

  5. Yang G, Yin S, Zhou R, Gu L, Yan B, Liu Y, Liu Y (1989) Studies of safe maximal daily dietary Se-intake in a seleniferous area in China. Part II: relation between Se-intake and the manifestation of clinical signs and certain biochemical alterations in blood and urine. J Trace Elem Electrolytes Health Dis 3:123–130

    PubMed  CAS  Google Scholar 

  6. Yang G, Zhou R, Yin S, Gu L, Yan B, Liu Y, Liu Y, Li X (1989) Studies of safe maximal daily dietary selenium intake in a seleniferous area in China. I. Selenium intake and tissue selenium levels of the inhabitants. J Trace Elem Electrolytes Health Dis 3:77–87

    PubMed  CAS  Google Scholar 

  7. Yang G, Zhou R (1994) Further observations on the human maximum safe dietary selenium intake in a seleniferous area of China. J Trace Elem Electrolytes Health Dis 8:159–165

    PubMed  CAS  Google Scholar 

  8. Yang GQ, Xia YM (1995) Studies on human dietary requirements and safe range of dietary intakes of selenium in China and their application in the prevention of related endemic diseases. Biomed Environ Sci 8:187–201

    PubMed  CAS  Google Scholar 

  9. Yang GQ, Wang SZ, Zhou RH, Sun SZ (1983) Endemic selenium intoxication of humans in China. Am J Clin Nutr 37:872–881

    PubMed  CAS  Google Scholar 

  10. Chylack LT Jr, Leske MC, McCarthy D, Khu P, Kashiwagi T, Sperduto R (1989) Lens opacities classification system II (LOCS II). Arch Ophthalmol 107:991–997

    PubMed  Google Scholar 

  11. Xu JJ, Yu Q, Zhu S et al (1994) Prevalence of lens opacity in natural population in Doumen County. Chin J Ophthalmol 30:225–227

    CAS  Google Scholar 

  12. Foster PJ, Wong TY, Machin D et al (2003) Risk factors for nuclear, cortical and posterior subcapsular cataracts in the Chinese population of Singapore: the Tanjong Pagar Survey. Br J Ophthalmol 87:1112–1120

    Article  PubMed  CAS  Google Scholar 

  13. Peters U, Foster CB, Chatterjee N, Schatzkin A, Reding D, Andriole GL, Crawford ED, Sturup S, Chanock SJ, Hayes RB (2007) Serum selenium and risk of prostate cancer—a nested case-control study. Am J Clin Nutr 85:209–217

    PubMed  CAS  Google Scholar 

  14. Hoffmann PR, Berry MJ (2008) The influence of selenium on immune responses. Mol Nutr Food Res. doi:10.1002/mnfr.200700330 [Epub ahead of print], Apr 2

  15. Dabbaghmanesh MH, Sadegholvaad A, Ejtehadi F, Omrani G (2007) Low serum selenium concentration as a possible factor for persistent goiter in Iranian school children. Biofactors 29:77–82

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Yiqiao Xing.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Li, T., He, T., Tan, X. et al. Prevalence of Age-Related Cataract in High-Selenium Areas of China. Biol Trace Elem Res 128, 1–7 (2009). https://doi.org/10.1007/s12011-008-8248-y

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12011-008-8248-y

Keywords

Navigation