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Adrenocorticotropic Hormone and Cortisol Levels in Athletes and Sedentary Subjects at Rest and Exhaustion: Effects of Magnesium Supplementation


The effects of a 1-month exercise program and magnesium supplementation on the adrenocorticotropic hormone and cortisol levels were studied in young tae-kwon-do and sedentary subjects both at rest and exhaustion. The hormone levels were compared before and after supplementation with 10 mg of magnesium (as magnesium sulfate) per kilogram of body weight. Both exercise and magnesium supplements caused significant increases of the adrenocorticotropic hormone (p < 0.05). The cortisol levels were increased in training subjects receiving supplements (p < 0.05) but not so in subjects that either trained or received magnesium supplements in an independent manner. The cortisol levels measured in resting individuals were higher in the supplemented and non-supplemented athletes than those in sedentary subjects (p < 0.05). The results of this study show that exercise and/or magnesium supplementation causes a rise of the adrenocorticotropic hormone, whereas cortisol is increased only as a result of combined exhaustion and magnesium supplements.

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Correspondence to Vedat Cinar.

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Cinar, V., Mogulkoc, R., Baltaci, A.K. et al. Adrenocorticotropic Hormone and Cortisol Levels in Athletes and Sedentary Subjects at Rest and Exhaustion: Effects of Magnesium Supplementation. Biol Trace Elem Res 121, 215–220 (2008).

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  • Tae-kwon-do
  • Magnesium supplementation
  • Rest
  • Exhaustion
  • ACTH
  • Cortisol