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Non-targeted Profiling of Sea Buckthorn Fruit Oil Fingerprints from 3 Regions and Study on Its Antioxidant Activity

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Abstract

This study investigated the chemical and volatile characteristics of sea buckthorn fruits from three different regions in China. The chemical composition of the volatile oil was determined by using a non-targeted gas chromatography and mass spectrometry (GC/MS) method and the differences in chemical composition among the three producing areas were compared by heatmap providing a visual basis for researchers. A total of 93 compounds were identified, including 52 compounds from the Northeast China, 51 from the Xinjiang region, and 37 from Inner Mongolia region. Then, the in vitro antioxidant activity of sea buckthorn fruit oil was measured using DPPH, ABTS, and SOD inhibition tests, and the results showed that sea buckthorn fruit oil in northeast China was the strongest antioxidant, followed by Inner Mongolia and Xinjiang. The results of the CCK-8 experiment indicated that within the tested concentration, there is no cell cytotoxicity of the essential oil in human umbilical vein endothelial cells (HUVECs) cells. The results could supply reference to distinguish sea buckthorn fruit from different production areas and, meanwhile, clarify the activity and safety of sea buckthorn oil.

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All the data obtained during this study are included in this article.

References

  1. Bakkali, F., Averbeck, S., Averbeck, D., & Idaomar, M. (2008). Food and Chemical Toxicology, 46, 446–475. https://doi.org/10.1016/j.fc-t.2007.09.106

    Article  CAS  PubMed  Google Scholar 

  2. Ashrafi, B., Marzieh, R., Gholami, E., Sattari, E., Marzban, A., Kheirandish, F., Khaksarian, M., Taherikalani, M., & Soroush, S. (2020). South African Journal of Botany, 135, 109–116. https://doi.org/10.1016/j.sajb.2020.08.015

    Article  CAS  Google Scholar 

  3. Zhang, N., & Yao, L. (2019). Journal of Agriculture and Food Chemistry, 67, 13790–13808. https://doi.org/10.1021/acs.jafc.9b00433

    Article  CAS  Google Scholar 

  4. Wang, N. N., Zheng, W. H., Zhang, K. X., Wen, X. F., Lu, S. G., & Yang, Z. G. (2021). China Journal of Chinese Materia Medica, 46(21), 5522–5532. https://doi.org/10.19540/j.cnki.cjcmm.20210520.201

    Article  CAS  PubMed  Google Scholar 

  5. Singh, S., & Sharma, P. C. (2022). Phytochemical Analysis PCA, 33(2), 214–225. https://doi.org/10.1002/pca.3081

    Article  CAS  PubMed  Google Scholar 

  6. Feng, X., Song, Z., Tao, A., Gong, P., Pei, W., & Zong, R. (2023). Frontiers in Nutrition, 10, 1136590. https://doi.org/10.3389/fnut.2023.1136590

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Wang, N., Wen, X., Gao, Y., Lu, S., Li, Y., Shi, Y., & Yang, Z. (2022). Frontiers in Nutrition, 9, 890486. https://doi.org/10.3389/fnut.2022.890486

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Fan, Y., Xin, X., Liu, L., Feng, H., Wang, P., Zhang, Y., & Gao, D. (2020). Chemistry & Biodiversity, 17(12), e2000666. https://doi.org/10.1002/cbdv.202000666

    Article  CAS  Google Scholar 

  9. Ashim, C. R., Abhinav, P., & Ilora, G. (2023). Applied Biochemistry and Biotechnology, 195, 172–195. https://doi.org/10.1007/s12010-022-04145-7

    Article  CAS  Google Scholar 

  10. Ashim, C. R., Abhinav, P., Komal, P., Priyanka, D., Shivangi, S., Chandra, G., Ilora, G. (2023). Biocatalysis and Agricultural Biotechnology, 50. https://doi.org/10.1016/j.bcab.2023.102674

  11. Baker, J. E. (1976). Plant Physiology, 58(5), 644–647. https://doi.org/10.1104/pp.58.5.644

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  12. Moon, J. Y., Jung, H. J., Moon, M. H., Chung, B. C., & Choi, M. H. (2009). Journal of the American Society for Mass Spectrometry, 20(9), 1626–1637. https://doi.org/10.1016/j.jasms.2009.9.04.020

    Article  CAS  PubMed  Google Scholar 

  13. Choudhury, T., Nigam, S., Dhasmana, S., Shamoon, M. (2021).Emerging technologies in data mining and information security. (Springer, Singapore, 2021), 815–826. https://doi.org/10.1007/978-981-15-9927-9_79

  14. Zhang, L., Qu, H., Liu, X., Li, Q., Liu, Y., Wang, W., Chen, D., Xiao, L., & Gu, R. (2022). Food Science & Nutrition, 10(12), 4247–4257. https://doi.org/10.1002/fsn3.3018

    Article  CAS  Google Scholar 

  15. Zajusz-Zubek, E., Mainka, A., & Kaczmarek, K. (2023). Dendrograms. Journal of Environmental Science and Health Part A, Toxic/Hazardous Substances & Environmental Engineering, 58(3), 163–170. https://doi.org/10.1080/10934529.2019.1670026

    Article  CAS  Google Scholar 

  16. HabibiNajafi, M. B., Leufven, A., EdalatianDovom, M. R., Sedaghat, N., & Pourfarzad, A. (2019). Food Science & Nutrition, 7, 2684–2691. https://doi.org/10.1002/fsn3.1124

    Article  CAS  Google Scholar 

  17. Wu, F., Liu, R., Shen, X., Xu, H., & Sheng, L. (2019). Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 215, 354–362. https://doi.org/10.1016/j.saa.2019.03.001

    Article  CAS  PubMed  Google Scholar 

  18. Aziz, Z. A. A., Ahmad, A., & Setapar, S. H. M. (2018). Current Drug Metabolism, 19, 1100–1110. https://doi.org/10.2174/1389200219666180723144850

    Article  CAS  PubMed  Google Scholar 

  19. Holmer, G., Kristensen, G., Sondergaard, E., Dam, H., Erziehwiss, Z. (1962) 2, 223–228. https://doi.org/10.1007/BF02020814

  20. Hutsell, T. C., & Quackenbush, F. W. (1967). Lipids, 2(4), 342–344. https://doi.org/10.1007/BF02532123

    Article  CAS  PubMed  Google Scholar 

  21. Walker, G., Flynn, P. F., & Kinsell, L. W. (1959). Lancet, 1(7067), 286–287. https://doi.org/10.1016/s0140-6736(59)90208-9

    Article  CAS  PubMed  Google Scholar 

  22. Hanssen, L., Warner, N. A., Braathen, T., Odland, J. Ø., Lund, E., Nieboer, E., & Sandanger, T. M. (2013). Environment International, 51, 82–87. https://doi.org/10.1016/j.envint.2012.10.008

    Article  CAS  PubMed  Google Scholar 

  23. Dudzina, T., von Goetz, N., Bogdal, C., Biesterbos, J. W., & Hungerbühler, K. (2014). Environment International, 62, 86–94. https://doi.org/10.1016/j.envint.2013.10.002

    Article  CAS  PubMed  Google Scholar 

  24. Boussaha, S., Bramucci, M., Rebbas, K., Quassinti, L., Mekkiou, R., Maggi, F. (2023). Natural Product Research, 1–7. https://doi.org/10.1080/14786419.2023.2176492

  25. Negm, W. A., Abo El-Seoud, K. A., Kabbash, A., Kassab, A. A., & El-Aasr, M. (2021). Natural Product Research, 35(23), 5166–5176. https://doi.org/10.1080/14786419.2020.1789636

    Article  CAS  PubMed  Google Scholar 

  26. Marangoni, F., Agostoni, C., Borghi, C., Catapano, A. L., Cena, H., Ghiselli, A., LaVecchia, C., Lercker, G., Manzato, E., Pirillo, A., Riccardi, G., Risé, P., Visioli, F., & Poli, A. (2020). Atherosclerosis, 292, 90–98. https://doi.org/10.1016/j.atherosclerosis.2019.11.018

    Article  CAS  PubMed  Google Scholar 

  27. Whelan, J., & Fritsche, K. (2013). Advances in Nutrition (Bethesda, Md.), 4(3), 311–312. https://doi.org/10.3945/an.113.003772

    Article  PubMed  Google Scholar 

  28. Hamilton, J. S., & Klett, E. L. (2021). Prostaglandins, Leukotrienes and Essential Fatty Acids, 175, 102366. https://doi.org/10.1016/j.plefa.2021.102366

    Article  CAS  PubMed  Google Scholar 

  29. Kim, K. B., Nam, Y. A., Kim, H. S., Hayes, A. W., & Lee, B. M. (2014). Food and Chemical Toxicology, 70, 163–178. https://doi.org/10.1016/j.fct.2014.05.009

    Article  CAS  PubMed  Google Scholar 

  30. Zhao, P., Wang, S., Liang, C., Wang, Y., Wen, P., Wang, F., & Qin, G. (2017). Regulatory Toxicology and Pharmacology, 91, 50–57. https://doi.org/10.1016/j.yrtph.2017.10.002

    Article  CAS  PubMed  Google Scholar 

  31. Wen, P., Zhao, P., Qin, G., Tang, S., Li, B., Zhang, J., & Peng, L. (2020). Drug and Chemical Toxicology, 43(4), 391–397. https://doi.org/10.1080/01480545.2018.1497047

    Article  CAS  PubMed  Google Scholar 

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Acknowledgements

This work has received strong support from the pharmaceutical research platform of Shandong University of Traditional Chinese Medicine.

Funding

This work was financially supported by Jinan “Twenty Rules for Colleges and Universities of Jinan” (No. 2020GXRC017) and Introduction and Education Program for young Talents in Shandong Colleges and Universities.

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Authors and Affiliations

  1. School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan City, China

    Ziyi Sun, Gaoning Zhang & Xiaoru Li

  2. School of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan City, China

    Qingqi Cui

  3. Experimental Center, Shandong University of Traditional Chinese Medicine, Jinan City, China

    Lili Gong & Zhenhua Tian

Authors
  1. Ziyi Sun
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  2. Gaoning Zhang
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  3. Xiaoru Li
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  4. Qingqi Cui
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  5. Lili Gong
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  6. Zhenhua Tian
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Contributions

All authors contributed to the study conception and design. Material preparation, data collection, and analysis were performed by ZS, GZ, XL, and QC. The first draft of the manuscript was written by ZS and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.

Corresponding authors

Correspondence to Lili Gong or Zhenhua Tian.

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Sun, Z., Zhang, G., Li, X. et al. Non-targeted Profiling of Sea Buckthorn Fruit Oil Fingerprints from 3 Regions and Study on Its Antioxidant Activity. Appl Biochem Biotechnol (2023). https://doi.org/10.1007/s12010-023-04744-y

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