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Casting Zinc Oxide Nanoparticles Using Fagonia Blend Microbial Arrest

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Abstract

Physical and chemical methods for production of nanoparticles (NPs) are not only harmful for environment but also toxic for living organism. The present study attempts to synthesize ZnO NPs using the natural plant extract of Fagonia cretica. The phytochemical screening of F. cretica water extract was performed to check the presence of biologically active compounds like alkaloids, tannins, carbohydrates, proteins, phenols, saponins, flavonoids, and steroids. Well-prepared ZnO NPs given sharp absorption peak at 362 were confirmed by UV–visible. XRD analysis showed the ZnO NPs having wurtzite hexagonal structure with crystalline form. TEM analysis endorses flower-shaped ZnO nanoparticles ~ 100–1000 nm. FTIR spectrum suggested the involvement of phenolic groups and amino acids and amide linkages in protein performs as the stabilizing agent in the synthesis of ZnO NPs. The ZnO NPs showed strong antibacterial behavior against two bacterial strains Gram-positive bacteria Staphylococcus aureus and Gram-negative bacteria Escherichia coli. In addition, ZnO NPs exhibited strong antioxidant activity of 79%:85.6%:89.9% at 5 μg/mL:10 μg/mL:5 μg/mL concentration of ZnO NPs respectively. This work indicates that Fagonia is considered to be appropriate and promising candidate for extending the innovative applications in the field of medicine and industry and also helpful and useful to the scientific communities.

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Authors and Affiliations

  1. Department of Zoology, Kohat University of Science and Technology, Kohat, 26000, Pakistan

    Riaz Hussain, Ayesha Zafar & Syed Ishtia Anjum

  2. Department of Biomedical Engineering, College of Future Technology, Peking University, Beijing, 100871, China

    Ayesha Zafar

  3. Department of Biotechnology, The Institute of Biochemistry, Biotechnology and Bioinformatics, The Islamia University of Bahawalpur, Bahawalpur, 63100, Pakistan

    Murtaza Hasan, Tuba Tariq, Muhamamd Saqib Saif, Muhammad Waqas, Fatima Tariq & Muniba Anum

  4. School of Chemistry and Chemical Engineering, Zhongkai University of Agriculture and Engineering, Guangzhou, 510225, China

    Murtaza Hasan & Xugang Shu

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Contributions

MH and SIA designed the experiment; RH and TT performed the experiments. AZ, MW, and MAN analyzed the results. RH wrote the manuscript. FT and MH edited the final version of the manuscript.

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Correspondence to Murtaza Hasan or Xugang Shu.

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Hussain, R., Zafar, A., Hasan, M. et al. Casting Zinc Oxide Nanoparticles Using Fagonia Blend Microbial Arrest. Appl Biochem Biotechnol 195, 264–282 (2023). https://doi.org/10.1007/s12010-022-04152-8

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