Effect of warming and buffering lidocaine on pain during facial anesthesia


In a double-blind study, room-temperature lidocaine was injected randomly into 1 eyelid of 40 patients during facial anesthesia. The other eyelid of the same eye received injection of warm lidocaine (group 1) or bicarbonate-buffered lidocaine (group 2). Based on a pain scale, warming or buffering lidocaine did not significantly reduce the amount of infiltration pain. Buffering lidocaine was effective in reducing the quality of pain, as judged by the patient's report of dominant pain.

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Correspondence to Haluk Talu MD.

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Talu, H., Elibol, O., Yanyali, A. et al. Effect of warming and buffering lidocaine on pain during facial anesthesia. Ann Ophthalmol 33, 43–47 (2001). https://doi.org/10.1007/s12009-001-0072-3

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  • Lidocaine
  • Pain Score
  • Bupivacaine
  • Cataract Surgery
  • Anesthetic Solution