Skip to main content
SpringerLink
Log in

Ocular lesions in generalized hallopeau-siemens type of recessive dystrophic epidermolysis bullosa

  • Case Report
  • Published:
Annals of Ophthalmology

Abstract

An infant was given a diagnosis of the Hallopeau-Siemens type recessive dystrophic epidermolysis bullosa shortly after birth, based on clinical, hereditary, and ultrastructural findings. At age 10 years, the boy complained of mild ocular pain. On examination, corneal opacities; erosion and blister in an eyelid; symblepharon; and occlusion of both upper lacrimal puncta were found. He had other findings consistent with the generalized Hallopeau-Siemens type, including dysplastic teeth and fusion of the toes.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Briggaman RA. Hereditary epidermolysis bullosa with special emphasis on newly recognized syndromes and complications. Dermatol Clin. 1983;1:263–280.

    Google Scholar 

  2. Cooper TW, Bauer EA. Epidermolysis bullosa: a review. Pediatr Dermatol. 1984;1:181–188.

    PubMed  CAS  Google Scholar 

  3. Fine JD, Epidermolysis bullosa: clinical aspects, pathology, and recent advances in research. Int J Dermatol. 1986;25:143–157.

    PubMed  CAS  Google Scholar 

  4. Gans LA. Eye lesions of epidermolysis bullosa: clinical features, management, and prognosis. Arch Dermatol. 1988;124:762–764.

    Article  PubMed  CAS  Google Scholar 

  5. Destro M, Wallow IHL, Brightbill FS. Recessive dystrophic epidermolysis bullosa. Arch Ophthalmol. 1987;105:1248–1252.

    PubMed  CAS  Google Scholar 

  6. McDonnell PJ, Spalton DJ. The ocular signs and complications of epidermolysis bullosa. J R Soc Med. 1988;81:576–578.

    PubMed  CAS  Google Scholar 

  7. Iwamoto M, Haik BG, Iwamoto T, Harrison W, Carter M. The ultrastructural defect in conjunctiva from a case of recessive dystrophic epidermolysis bullosa. Arch Ophthalmol. 1991;109:1382–1386.

    PubMed  CAS  Google Scholar 

  8. Hashimoto I, Schnyder UW, Anton-Lamprecht I, Gedde-Dahl T Jr, Ward S. Ultrastructural studies in epidermolysis bullosa hereditaria: III. Recessive dystrophic types with dermolytic blistering (Hallopeau-Siemens types and inverse type). Arch Dermatol Res. 1976;256:137–150.

    Article  PubMed  CAS  Google Scholar 

  9. Takahashi T, Shimao S, Imamura H, et al. A case of dystrophic epidermolysis bullosa [in Japanese]. Shonika-Rinsho. 1989;42:1261–1265.

    Google Scholar 

  10. Michaelson JD, Schmidt JD, Dresden MH, Duncan C. Vitamin E treatment of epidermolysis bullosa: changes in tissue collagenase levels. Arch Dermatol. 1974;109:67–69.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Ophthalmology, Toyama Medical and Pharmaceutical University, 2630 Sugitani, 930-0194, Toyama, Japan

    Yoriko Hayasaka MD, Seiji Hayasaka MD, Konomi Watanabe MD, Chihiro Matsui MD & Chiharu Kadoi MD

Authors
  1. Yoriko Hayasaka MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Seiji Hayasaka MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Konomi Watanabe MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Chihiro Matsui MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Chiharu Kadoi MD
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hayasaka, Y., Hayasaka, S., Watanabe, K. et al. Ocular lesions in generalized hallopeau-siemens type of recessive dystrophic epidermolysis bullosa. Ann Ophthalmol 33, 326–329 (2001). https://doi.org/10.1007/s12009-001-0049-2

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12009-001-0049-2

Keywords

Search

Navigation