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Do Survival Rate and Serum Ion Concentrations 10 Years After Metal-on-Metal Hip Resurfacing Provide Evidence for Continued Use?

  • Symposium: Papers Presented at the 2011 Meeting of the International Hip Society
  • Published:
Clinical Orthopaedics and Related Research®

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Abstract

Background

Owing to concerns attributable to problems associated with metal-on-metal bearing surfaces, current evidence for the use of hip resurfacing is unclear. Survival rates reported from registries and individual studies are controversial and the limited long-term studies do not conclusively allow one to judge whether hip resurfacing is still a reasonable alternative to conventional THA.

Questions/purposes

We asked whether the long-term survival rate of hip resurfacing is comparable to that of conventional THA and certain factors can be identified that influence serum ion concentration 10 years postoperatively. We specifically assessed (1) the 10-year survivorship in the whole cohort and in male and female patients, (2) serum concentrations of metal ions in patients with hip resurfacing who had not undergone revision surgery, and (3) potential influencing factors on the serum ion concentration.

Methods

We retrospectively reviewed our first 95 patients who had 100 hip resurfacings performed from 1998 to 2001. The median age of the patients at surgery was 52 years (range, 28–69 years); 49% were men. We assessed the survival rate (revision for any reason as the end point), radiographic changes, and serum ion concentrations for cobalt, chromium, and molybdenum. The correlations between serum ion concentration and patient-related factors (age, sex, BMI, activity) and implant-related factors (implant size, cup inclination, stem-shaft angle) were investigated. The minimum followup was 9.3 years (mean, 10 years; range, 9.3–10.5 years).

Results

The 10-year survivorship was 88% for the total cohort. The overall survival rate was greater in men (93%) than in women (84%). Median serum ion levels were 1.9 μg/L for chromium, 1.3 μg/L for cobalt, and 1.6 μg/L for molybdenum. Radiolucent lines around acetabular implants were observed in 4% and femoral neck thinning in 5%.

Conclusions

Although our overall failure rate was greater than anticipated, the relatively low serum ion levels and no revisions for pseudotumors in young male patients up to 10 years postoperatively provide some evidence of the suitability of hip resurfacing in this subgroup.

Level of Evidence

Level IV, therapeutic study. See the Instructions for Authors for a complete description of levels of evidence.

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References

  1. Akbar M, Brewer JM, Grant MH. Effect of chromium and cobalt ions on primary human lymphocytes in vitro. J Immunotoxicol. 2011:8:140–149.

    Article  PubMed  CAS  Google Scholar 

  2. Amstutz HC, Beaule PE, Dorey FJ, Le Duff MJ, Campbell PA, Gruen TA. Metal-on-metal hybrid surface arthroplasty: two to six-year follow-up study. J Bone Joint Surg Am. 2004:86:28–39.

    PubMed  Google Scholar 

  3. Amstutz HC, Le Duff MJ, Campbell PA, Gruen TA, Wisk LE. Clinical and radiographic results of metal-on-metal hip resurfacing with a minimum ten-year follow-up. J Bone Joint Surg Am. 2010:92:2663–2671.

    Article  PubMed  Google Scholar 

  4. Australian Orthopaedic Association National Joint Replacement Registry. Hip and Knee Arthroplasty, Annual Report 2010. Available at: http://www.dmac.adelaide.edu.au/aoanjrr/publications.jsp?section=reports2010. Accessed June 5, 2011.

  5. Baker RP, Pollard TC, Eastaugh-Waring SJ, Bannister GC. A medium-term comparison of hybrid hip replacement and Birmingham hip resurfacing in active young patients. J Bone Joint Surg Br. 2011:93:158–163.

    Article  PubMed  CAS  Google Scholar 

  6. Beaule PE, Dorey FJ, Hoke R, Le DM, Amstutz HC. The value of patient activity level in the outcome of total hip arthroplasty. J Arthroplasty. 2006:21:547–552.

    Article  PubMed  Google Scholar 

  7. Beaule PE, Dorey FJ, Le Duff MJ, Gruen T, Amstutz HC. Risk factors affecting outcome of metal-on-metal surface arthroplasty of the hip. Clin Orthop Relat Res. 2004:418:87–93.

    Article  PubMed  Google Scholar 

  8. Beaule PE, Kim PR, Powell J, Mackenzie J, Werle J, Antoniou J, Huk O, Vendittoli PA, Lavigne M, Smith F, Naudie D, McCalden R, Bourne R, Schemitsch E, Garbuz D, Greidanus N, Duncan C, Belzile E; Canadian Hip Resurfacing Study Group. A survey on the prevalence of pseudotumors with metal-on-metal hip resurfacing in Canadian academic centers. J Bone Joint Surg Am. 2011:93(suppl 2):118–121.

    Article  Google Scholar 

  9. Corten K, MacDonald SJ. Hip resurfacing data from national joint registries: what do they tell us? What do they not tell us? Clin Orthop Relat Res. 2010:468:351–357.

    Article  PubMed  Google Scholar 

  10. Daniel J, Pynsent PB, McMinn DJ. Metal-on-metal resurfacing of the hip in patients under the age of 55 years with osteoarthritis. J Bone Joint Surg Br. 2004:86:177–184.

    Article  PubMed  CAS  Google Scholar 

  11. Daniel J, Ziaee H, Kamali A, Pradhan C, Band T, McMinn DJ. Ten-year results of a double-heat-treated metal-on-metal hip resurfacing. J Bone Joint Surg Br. 2010:92:20–27.

    Article  PubMed  CAS  Google Scholar 

  12. Daniel J, Ziaee H, Pradhan C, McMinn DJ. Six-year results of a prospective study of metal ion levels in young patients with metal-on-metal hip resurfacings. J Bone Joint Surg Br. 2009:91:176–179.

    PubMed  CAS  Google Scholar 

  13. Desy NM, Bergeron SG, Petit A, Huk OL, Antoniou J. Surgical variables influence metal ion levels after hip resurfacing. Clin Orthop Relat Res. 2011:469:1635–1641.

    Article  PubMed  Google Scholar 

  14. Glyn-Jones S, Pandit H, Kwon YM, Doll H, Gill HS, Murray DW. Risk factors for inflammatory pseudotumour formation following hip resurfacing. J Bone Joint Surg Br. 2009:91:1566–1574.

    Article  PubMed  CAS  Google Scholar 

  15. Griffin WL, Nanson CJ, Springer BD, Davies MA, Fehring TK. Reduced articular surface of one-piece cups: a cause of runaway wear and early failure. Clin Orthop Relat Res. 2010:468:2328–2332.

    Article  PubMed  Google Scholar 

  16. Grigoris P, Roberts P, Panousis K. The development of the Durom™ metal-on-metal hip resurfacing. Hip Int. 2006:16(suppl 4):65–72.

    PubMed  Google Scholar 

  17. Haddad FS, Thakrar RR, Hart AJ, Skinner JA, Nargol AV, Nolan JF, Gill HS, Murray DW, Blom AW, Case CP. Metal-on-metal bearings: the evidence so far. J Bone Joint Surg Br. 2011:93:572–579.

    PubMed  CAS  Google Scholar 

  18. Harris WH. Traumatic arthritis of the hip after dislocation and acetabular fractures: treatment by mold arthroplasty: an end-result study using a new method of result evaluation. J Bone Joint Surg Am. 1969:51:737–755.

    PubMed  CAS  Google Scholar 

  19. Hart AJ, Skinner JA, Henckel J, Sampson B, Gordon F. Insufficient acetabular version increases blood metal ion levels after metal-on-metal hip resurfacing. Clin Orthop Relat Res. 2011:469:2590–2597.

    Article  PubMed  Google Scholar 

  20. Kwon YM, Ostlere SJ, Lardy-Smith P, Athanasou NA, Gill HS, Murray DW. “Asymptomatic” pseudotumors after metal-on-metal hip resurfacing arthroplasty: prevalence and metal ion study. J Arthroplasty. 2011:26:511–518.

    Article  PubMed  Google Scholar 

  21. Langton DJ, Jameson SS, Joyce TJ, Gandhi JN, Sidaginamale R, Merredy P, Lord J, Nargol AV. Accelerating failure rate of the ASR total hip replacement. J Bone Joint Surg Br. 2011:93:1011–1016.

    Article  PubMed  CAS  Google Scholar 

  22. Langton DJ, Jameson SS, Joyce TJ, Hallab NJ, Natu S, Nargol AV. Early failure of metal-on-metal bearings in hip resurfacing and large-diameter total hip replacement: a consequence of excess wear. J Bone Joint Surg Br. 2010:92:38–46.

    Article  PubMed  CAS  Google Scholar 

  23. Langton DJ, Joyce TJ, Jameson SS, Lord J, Van Orsouw M, Holland JP, Nargol AV, De Smet KA. Adverse reaction to metal debris following hip resurfacing: the influence of component type, orientation and volumetric wear. J Bone Joint Surg Br. 2011:93:164–171.

    Article  PubMed  CAS  Google Scholar 

  24. Langton DJ, Sprowson AP, Joyce TJ, Reed M, Carluke I, Partington P, Nargol AV. Blood metal ion concentrations after hip resurfacing arthroplasty: a comparative study of articular surface replacement and Birmingham Hip Resurfacing arthroplasties. J Bone Joint Surg Br. 2009:91:1287–1295.

    Article  PubMed  CAS  Google Scholar 

  25. Lingard EA, Muthumayandi K, Holland JP. Comparison of patient-reported outcomes between hip resurfacing and total hip replacement. J Bone Joint Surg Br. 2009:91:1550–1554.

    Article  PubMed  CAS  Google Scholar 

  26. Lugowski SJ, Smith DC, McHugh AD, Van Loon JC. Determination of chromium, cobalt and molybdenum in synovial fluid by GFAAS. J Trace Elem Electrolytes Health Dis. 1991:5:23–29.

    PubMed  CAS  Google Scholar 

  27. McArthur JR, Costa M, Griffin DR, Krikler SJ, Parsons N, Foguet PR. Groin pain following hip resurfacing: a case-control study. Hip Int. 2011:21:602–609.

    Article  PubMed  Google Scholar 

  28. McBryde CW, Revell MP, Thomas AM, Treacy RB, Pynsent PB. The influence of surgical approach on outcome in Birmingham Hip Resurfacing. Clin Orthop Relat Res. 2008:466:920–926.

    Article  PubMed  Google Scholar 

  29. McGrory B, Barrack R, Lachiewicz PF, Schmalzried T, Yates AJ, Watters WC, Turkelson CM, Wies JL, Andre JS. Modern metal-on-metal hip resurfacing. J Am Acad Orthop Surg. 2010:18:306–314.

    PubMed  Google Scholar 

  30. Mont MA, Seyler TM, Ulrich SD, Beaule PE, Boyd HS, Grecula MJ, Goldberg VM, Kennedy WR, Marker DR, Schmalzried T, Sparling EA, Vail TP, Amstutz HC. Effect of changing indications and techniques on total hip resurfacing. Clin Orthop Relat Res.2007:465:63–70.

    PubMed  Google Scholar 

  31. Murray DW, Carr AJ, Bulstrode C. Survival analysis of joint replacements. J Bone Joint Surg Br. 1993:75:697–704.

    PubMed  CAS  Google Scholar 

  32. Murray DW, Grammatopoulos G, Gundle R, Gibbons CL, Whitwell D, Taylor A, Glyn-Jones S, Pandit HG, Ostlere S, Gill HS, Athanasou N, McLardy-Smith P. Hip resurfacing and pseudotumour. Hip Int. 2011:21:279–283.

    Article  PubMed  Google Scholar 

  33. National Institute for Clinical Excellence. Guidance on the selection of prostheses for primary total hip replacement (TA2). Available at: http://www.nice.org.uk. Accessed October 8, 2011.

  34. Nishii T, Sugano N, Miki H, Takao M, Koyama T, Yoshikawa H. Five-year results of metal-on-metal resurfacing arthroplasty in Asian patients. J Arthroplasty. 2007:22:176–183.

    Article  PubMed  Google Scholar 

  35. Nunley RM, Zhu J, Brooks PJ, Engh CA, Raterman SJ, Rogerson JS, Barrack RL. The learning curve for adopting hip resurfacing among hip specialists. Clin Orthop Relat Res. 2010:468:382–391.

    Article  PubMed  Google Scholar 

  36. Olsen M, Davis ET, Gallie PA, Waddell JP, Schemitsch EH. The reliability of radiographic assessment of femoral neck-shaft and implant angulation in hip resurfacing arthroplasty. J Arthroplasty. 2009:24:333–340.

    Article  PubMed  Google Scholar 

  37. Pandit H, Glyn-Jones S, McLardy-Smith P, Gundle R, Whitwell D, Gibbons CL, Ostlere S, Athanasou N, Gill HS, Murray DW. Pseudotumours associated with metal-on-metal hip resurfacings. J Bone Joint Surg Br. 2008:90:847–851.

    Article  PubMed  CAS  Google Scholar 

  38. Prohaska C, Pomazal K, Steffan I. ETAAS method for the determination of Cd, Cr, Cu, Mn and Se in blood fractions and whole blood. Fresenius J Anal Chem. 2000:368:627–632.

    Article  PubMed  CAS  Google Scholar 

  39. Prosser GH, Yates PJ, Wood DJ, Graves SE, Steiger RN, Miller LN. Outcome of primary resurfacing hip replacement: evaluation of risk factors for early revision. Acta Orthop. 2010:81:66–71.

    Article  PubMed  Google Scholar 

  40. Reito A, Puolakka T, Paakkala A, Pajamaki J. Assessment of inter- and intra-observer reliability in the determination of radiographic version and inclination of the cup in metal-on-metal hip resurfacing. Int Orthop. 2012;36:519–525.

    Article  PubMed  Google Scholar 

  41. Shimmin A, Beaule PE, Campbell P. Metal-on-metal hip resurfacing arthroplasty. J Bone Joint Surg Am. 2008:90:637–654.

    Article  PubMed  Google Scholar 

  42. Shimmin AJ, Back D. Femoral neck fractures following Birmingham Hip Resurfacing: a national review of 50 cases. J Bone Joint Surg Br. 2005:87:463–464.

    Article  PubMed  CAS  Google Scholar 

  43. Smith TO, Nichols R, Donell ST, Hing CB. The clinical and radiological outcomes of hip resurfacing versus total hip arthroplasty: a meta-analysis and systematic review. Acta Orthop. 2010:81:684–695.

    Article  PubMed  Google Scholar 

  44. Springer BD, Connelly SE, Odum SM, Fehring TK, Griffin WL, Mason JB, Masonis JL. Cementless femoral components in young patients: review and meta-analysis of total hip arthroplasty and hip resurfacing. J Arthroplasty. 2009:24:2–8.

    Article  PubMed  Google Scholar 

  45. Swedish Hip Arthroplasty Register. Annual Report 2008. Available at: https://www.jru.orthop.gu.se. Accessed: October 8, 2011.

  46. Treacy RB, McBryde CW, Pynsent PB. Birmingham Hip Resurfacing arthroplasty: a minimum follow-up of five years. J Bone Joint Surg Br. 2005:87:167–170.

    Article  PubMed  CAS  Google Scholar 

  47. Treacy RB, McBryde CW, Shears E, Pynsent PB. Birmingham Hip Resurfacing: a minimum follow-up of ten years. J Bone Joint Surg Br. 2011:93:27–33.

    Article  PubMed  CAS  Google Scholar 

  48. Van der Weegen W, Hoekstra HJ, Sijbesma T, Bos E, Schemitsch EH, Poolman RW. Survival of metal-on-metal hip resurfacing arthroplasty: a systematic review of the literature. J Bone Joint Surg Br. 2011:93:298–306.

    Article  PubMed  Google Scholar 

  49. Vendittoli PA, Mottard S, Roy AG, Dupont C, Lavigne M. Chromium and cobalt ion release following the Durom high carbon content, forged metal-on-metal surface replacement of the hip. J Bone Joint Surg Br. 2007:89:441–448.

    Article  PubMed  Google Scholar 

  50. Witzleb WC, Arnold M, Krummenauer F, Knecht A, Ranisch H, Guenther KP. Birmingham Hip Resurfacing arthroplasty: short-term clinical and radiographic outcome. Eur J Med Res. 2008:13:39–46.

    PubMed  Google Scholar 

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Acknowledgments

We thank our medical documentation assistants, Heike Voigt, Brit Brethfeld, and Susann Pohle, for assistance in collecting data. We also thank Gerd Dinnebier MD for his methodologic support with serum ion measurement.

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Corresponding author

Correspondence to Klaus-Peter Günther MD.

Additional information

The institution of one or more of the authors has received, in any 1 year, funding from Aesculap AG & Co KG, Tuttlingen, Germany (JL), Mathys AG, Bettlach, Switzerland (JL, SK), Smith & Nephew GmbH, Marl, Germany (JL, KPG, WCW), Stryker GmbH & Co KG, Freiburg, Germany (JL, SK, KPG), Zimmer GmbH, Winterthur, Switzerland (KPG, SK), and Deutsche Arthrose-Hilfe, Frankfurt/Main, Germany (KPG, SK).

All ICMJE Conflict of Interest Forms for authors and Clinical Orthopaedics and Related Research editors and board members are on file with the publication and can be viewed on request.

Clinical Orthopaedics and Related Research neither advocates nor endorses the use of any treatment, drug, or device. Readers are encouraged to always seek additional information, including FDA approval status, of any drug or device before clinical use.

Each author certifies that his or her institution approved the human protocol for this investigation, that all investigations were conducted in conformity with ethical principles of research, and that informed consent for participation in the study was obtained.

This work was performed at the University Hospital Carl Gustav Carus Dresden, Dresden, Germany.

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Hartmann, A., Lützner, J., Kirschner, S. et al. Do Survival Rate and Serum Ion Concentrations 10 Years After Metal-on-Metal Hip Resurfacing Provide Evidence for Continued Use?. Clin Orthop Relat Res 470, 3118–3126 (2012). https://doi.org/10.1007/s11999-012-2329-0

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