Abstract
In this study, the synthesis of cyclodextrin-based hyperbranched polyester (CD-based HBPE) was prepared by a simple condensation route via acid chloride approach (Scheme 1). The formation of ester linkages in CD-based HBPE was clearly identified from FTIR and NMR spectroscopy. The resulting structure and the molecular weight of the CD-based HBPE were confirmed with LC–MS analysis. The CD-based HBPE displayed the fluorescence maxima in the 425 nm range with relatively narrow peak widths indicating that they had pure and intense fluorescence. The antimicrobial activity of the CD-based HBPE was evaluated against the Gram-negative organisms like Escherichia coli and Salmonella paratyphi, Gram-positive organisms as Bacillus subtilis and Staphylococcus aureus and fungi such as Aspergillus niger, and Candida albicans. CD-based HBPE showed a great inhibitory effect toward both bacteria and fungi. The microorganism which possess greater antimicrobial activity with standard antibiotics was selected for determining the minimum inhibitory concentration (MIC) value of the CD-based HBPE. Therefore, the MIC value of the CD-based HBPE against B. subtilis was tested and found to be 31.25 μg mL−1. Hence, it is suggested that CD-based HBPE holds good agreement with the antimicrobial assay.
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The authors gratefully acknowledge the Sri Krishna College of Technology and Bharathiar University for their constant support.
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Fig. S3 Cyclic voltammograms of the CD-based HBPE in toluene/acetonitrile (v/v 8:2) containing 0.1 M TBAP at a scan rate of 10 mV/s, vs Ag/AgCl (EPS 730 kb)
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Prabu, S., Sivakumar, C. Cyclodextrin-based hyperbranched polyester: synthesis, characterization, and antimicrobial activity. J Coat Technol Res 15, 1059–1066 (2018). https://doi.org/10.1007/s11998-017-0041-4
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DOI: https://doi.org/10.1007/s11998-017-0041-4