Skip to main content
Log in

Acute treatment of spinal cord injury

  • Published:
Current Treatment Options in Neurology Aims and scope Submit manuscript

Opinion statement

  • •At the authors’ institution, a multidisciplinary team of trauma physicians, neurosurgeons, and anesthesiologists evaluates patients with suspected spinal cord injury. Our initial goal after resuscitation and evaluation is to assure adequate tissue oxygenation through blood pressure support and oxygen supplementation. This supplementation helps ensure maximal oxygen delivery to the injured spinal cord. It is important that a detailed and standardized neurologic examination is performed and repeated often to detect neurologic decline.

  • •Immediately after a potential spinal cord injury is identified, methylprednisolone is administered (ideally during transport from the accident scene).

  • •Plain x-rays of the spine are the first films obtained. Once a fracture is identified, a computerized CT scan through the identified region is done. If the injury involves the cervical spine, and reduction is needed to correct a deformity, closed reduction with placement of a halo-fixation device is performed in the emergency room. We believe that reduction to normal spinal alignment should be accomplished within a few hours of the injury. Once initial immobilization efforts are complete, the patient gets an magnetic resonance image (MRI) of the affected region.

  • •Most spinal cord injury patients at our institution do not undergo emergency surgery. Urgent surgery is only performed in those with continued neurologic decline, and MRI findings of acute compression from lesions such as a ruptured disc or epidural hematoma.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Benxel EC, Tator CH: Contemporary Management of Spinal Cord Injury (Neurosurgical Topics). Park Ridge: American Association of Neurological Surgeons; 1995. Provides a comprehensive review of spinal cord injury from the emergency room to rehabilitation.

    Google Scholar 

  2. Buchanan LE, Nawoczenski DA: Spinal Cord Injury Concepts and Management Approaches. Baltimore: Williams & Wilkins; 1987.

    Google Scholar 

  3. Fehlings MG, Tator CH: An evidence-based review of decompressive surgery in acute spinal cord injury: rationale, indications, and timing based on experimental and clinical studies. J. Neurosurg 1999, 91:1–18. Provides evidenced-based data on all aspects of surgical care.

    PubMed  CAS  Google Scholar 

  4. Hadley MN: Injuries to the cervical spine. In Principles of Neurosurgery. Edited by Rengachary SS, Wilkins RH. London: Mosby Wolfe; 1994: 20.2–20.13.

    Google Scholar 

  5. Dyson-Hhudson TA, Stein AB: Acute management of traumatic cervical spinal cord injuries. Mount Sinai J Med 1999, 66(3):170–178.

    CAS  Google Scholar 

  6. Yu D: A crash course in spinal cord injury. Postgrad Med 1998, 104(2):109–122.

    PubMed  CAS  Google Scholar 

  7. Delamarter RB, Coyle J: Acute management of spinal cord injury. J Am Acad Orthop Surg 1999, 7(3):166–175.

    PubMed  CAS  Google Scholar 

  8. Benzel EC: Management of acute spinal cord injury, In Neurosurgery, vol 2. Edited by Wilkins RH, Rengachary SS. New York: McGraw Hill; 1996:2861–2865.

    Google Scholar 

  9. Bracken MB, Shepard MJ, Collins WF, et al.: A randomized, controlled trial of methylprednisolone or naloxone in the treatment acute spinal-cord injury. Results of the second national acute spinal cord injury study. N Engl J Med 1990, 322(20):1405–1411. Because of this trial, methylprednisolone has become standard care in the treatment of spinal cord injury.

    Article  PubMed  CAS  Google Scholar 

  10. Heary RF, Vaccaro AR, Mesa JJ, et al.: Steroids and gunshot wounds to the spine. Neurosurgery 1997, 41(3):576–583.

    Article  PubMed  CAS  Google Scholar 

  11. Walker JB, Harris M: GM-1 ganglioside administration combined with physical therapy restores ambulation in humans with chronic spinal cord injury. Neurosci Lett 1993, 161(2):174–178.

    Article  PubMed  CAS  Google Scholar 

  12. Geisler FH, Dorsey FC, Coleman WP: Recovery of motor function after spinal-cord injury—a randomized placebo controlled trial with GM-1 ganglioside. N Engl J Med 1991, 324(26):1829–1838.

    Article  PubMed  CAS  Google Scholar 

  13. Constantini S, Young W: The effects of methylprednisolone and the ganglioside GM1 on acute spinal cord injury in rats. J Neurosurg 1994, 80(1):97–111.

    Article  PubMed  CAS  Google Scholar 

  14. Bracken MB, Shepard MJ, Holford TR, et al.: Administration of methylprednisolone for 24 or 48 hours or tirilazad mesylate for 48 hours in the treatment of acute spinal cord injury. Results of the third national acute spinal cord injury randomized control trial. JAMA 1997, 277(20):1597–1604.

    Article  PubMed  CAS  Google Scholar 

  15. Fleishaker JC, Pearson LK, Peters GR: Induction of tirilazad clearance by phenytoin. Biopharm Drug Dispos 1998, 19(2):91–96.

    Article  PubMed  CAS  Google Scholar 

  16. Waters RL, Adkins RH, Yakura JS, Sei I: Effect of surgery on motor recovery following traumatic spinal cord injury. Spinal Cord 1996, 34(4):188–192.

    PubMed  CAS  Google Scholar 

  17. Vaccaro AR, Daugherty AJ, Sheehan TP, et al.: Neurologic outcome of early versus late surgery for cervical spinal cord injury. Spine 1997, 22(22):2609–2613.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Esce, P.G., Haines, S.J. Acute treatment of spinal cord injury. Curr Treat Options Neurol 2, 517–524 (2000). https://doi.org/10.1007/s11940-000-0030-1

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11940-000-0030-1

Keywords

Navigation