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Vaccine therapy for colon cancer

Current Treatment Options in Gastroenterology volume 2, pages 343–348 (1999)Cite this article

Conclusions

A meta-analysis of all three trials with 723 patients has been concluded, and is currently being submitted for publication. Our conclusions at this point are that the data are sufficiently compelling to suggest that active specific immunotherapy with an autologous tumor cell plus BCG vaccine should be considered as a standard therapy for patients with stage II colon cancer. A phase III trial in Stage III colon cancer comparing surgical resection followed by six months of 5-FU/leucovorin chemotherapy followed by a fourth vaccine boost at 6 months versus surgical resection alone, is being started in Europe and the United States.

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Authors and Affiliations

  1. Department of Surgery, Lehigh Valley Hospital, Cedar Crest & I-78, PO Box 689, 18105-1556, Allentown, PA

    Herbert C. Hoover Jr MD

Authors
  1. Herbert C. Hoover Jr MD
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  2. Michael G. Hanna Jr PhD
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Hoover, H.C., Hanna, M.G. Vaccine therapy for colon cancer. Curr Treat Options Gastro 2, 343–348 (1999). https://doi.org/10.1007/s11938-999-0023-4

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  • DOI: https://doi.org/10.1007/s11938-999-0023-4