Current Treatment Options in Gastroenterology

, Volume 2, Issue 4, pp 337–341 | Cite as

Medical therapy for cholesterol-gallstones: A role of statins?

  • Gerald Salen
  • Ashok K. Batta
Article
  • 36 Downloads

Opinion Statement

The combination of statin drugs with ursodiol for the dissolution of cholesterol gallstones may be more effective than monotherapy alone. Adding a statin drug that inhibits HMG-CoA reductase may reduce biliary cholesterol so that the combination with ursodiol produces the maximum decrease in biliary cholesterol secretion. The major disadvantage is the added cost of using two drugs.

Keywords

Bile Acid Pravastatin Cholic Acid Ursodeoxycholic Acid Chenodeoxycholic Acid 

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Copyright information

© Current Science Inc 1999

Authors and Affiliations

  • Gerald Salen
    • 1
  • Ashok K. Batta
  1. 1.Division of GastroenterologyUMDNJ, New Jersey Medical SchoolNewark

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